In heart failure, impairment of cardiac muscle function leads to numerous neurohormonal and metabolic disorders, including an imbalance between anabolic and catabolic processes, in favour of the latter. These disorders cause loss of muscle mass with structural and functional changes within the skeletal muscles, known as skeletal myopathy. This phenomenon constitutes an important mechanism that ...

Dimorphism on dominance and agonistic behaviour in mammals tends to be strongly biased toward males. In this review, we focus on a select few species of mammals in which females are as or more aggressive than males, and/or are dominant to males, and explore the role of androgenic hormones in mediating this important difference. While the data are not as clear-cut as those published on tradition...

Androgen insensitivity syndrome (AIS) is a condition that results in the partial or complete inability of the cell to respond to androgens (androgenic hormones) that stimulate or control the development and maintenance of male physiological characteristics by binding to androgen receptors. The unresponsiveness of the cell to the presence of androgenic hormones can impair, or prevent, both the m...

Fungal growth can be influenced by human physiological mediators such as androgenic hormones. The aim of this study was to investigate a possible relationship between androgenic hormones and susceptibility to dermatophytosis. To this purpose we measured the levels of testosterone, androstendione, and dehydroepianderosterone sulfate (DHEA-S) in 60 male patients with dermatophytosis due to Epider...

SYNOPSIS. The androgenic gland has been described in a variety of crustacean species—isopods, amphipods and decapods. It has been shown to play a role in the regulation of male differentiation and in the inhibition of female differentiation. Upon its application for endocrine manipulation, it inhibits female characteristics. Recently, the androgenic hormone from the isopod Armadillidium vulgare...

Over the last decade, research has examined the endocrine-disrupting action of various environmental pollutants, including hormones, pharmaceuticals, and surfactants, in sewage treatment plant effluent. Responding to the growth of concentrated animal feeding operations (CAFOs) and the pollutants present in their wastewater (e.g., nutrients, pharmaceuticals, and hormones), the U.S. Environmental...

T HE EFFECT OF ANDROGENIC STEROIDS on hemoglobin levels has usually been ascribed to an indirect effect of these hormones, possibly secondary to an effect upon erythropoietin production or activation.1’2 Earlier studies of the in vitro effect of androgens on bone marrow cells provided conflicting evidence for a direct effect upon erythroid cell proliferation or hemoglobin synthesis. Reisner3 pr...

T HE EFFECT OF ANDROGENIC STEROIDS on hemoglobin levels has usually been ascribed to an indirect effect of these hormones, possibly secondary to an effect upon erythropoietin production or activation.1’2 Earlier studies of the in vitro effect of androgens on bone marrow cells provided conflicting evidence for a direct effect upon erythroid cell proliferation or hemoglobin synthesis. Reisner3 pr...