quantitative structure-activity relationship (qsar) studies of a series of substituted 3-hydroxy-pyridine-4-ones and 3-hydroxy-pyran-4-ones as antibacterial and antifungal agents against a variety of microorganisms were performed. multiple linear regression approach was used as variable selection method. the antimicrobial activities of these compounds against staphylococcus aureus, aspergilus n...

the objective of the present study was to prepare controlled release formulation of moxifloxacin hydrochloride ocular nanoparticles. the nanoparticles were prepared by solvent displacement method using eudragit rl 100 as a polymer. different formulations were prepared by varying the ratios of drug and polymer and varying the ratios of organic and aqueous phase. the formulations were evaluated i...

aqueous extract and volatile oil were obtained from miliusa tomentosa by using soxhlet extractor and hydro distillation with a clevenger-type apparatus respectively. the extract and volatile oil both were screened for antimicrobial activity against different bacteria (escherichia coli, staphylococcus aureus, bacillus subtilis, klebsiella pncumoniae, pseudomonas aeruginosa, bacillus pumilis) and...

background and objectives: food poisoning has been always a major concern in health system of every community and cream-filled products are one of the most widespread food poisoning causes in humans. in present study, we examined the preservative effect of the cinnamon oil in cream-filled cakes. methods: antimicrobial activity of cinnamomum verum j. presl (cinnamon) bark essential oil was examin...

in different folk medicine ziziphus spina-christi is used for different purposes such as pneumonia, dysentery, scorpion stings, cough, constipation, intestinal worms and fever. the aim of this study was evaluation and comparing the antibacterial activity of methanolic and ethanolic extracts of ziziphus spina –christi as well as subsequent structural changes in affected bacteria. for this purpos...

The objective of the present study was to prepare controlled release formulation of Moxifloxacin hydrochloride ocular nanoparticles. The nanoparticles were prepared by solvent displacement method using Eudragit RL 100 as a polymer. Different formulations were prepared by varying the ratios of drug and polymer and varying the ratios of organic and aqueous phase. The formulations were evaluated i...

The objective of the present study was to prepare controlled release formulation of Moxifloxacin hydrochloride ocular nanoparticles. The nanoparticles were prepared by solvent displacement method using Eudragit RL 100 as a polymer. Different formulations were prepared by varying the ratios of drug and polymer and varying the ratios of organic and aqueous phase. The formulations were evaluated i...

Nowadays silver nanoparticles (AgNPs) are used as antimicrobial due to its well known physical, chemical, and biological properties. A large collection of bacterial cells adhering to a surface is called bacterial biofilm. Exposure to silver nano particles (AgNPs) may prevent colonization of new bacteria onto the biofilm. In the present work, we have investigated whether the biofilm format...