The ability of neurons to differentially respond to specific temporal and spatial input patterns underlies information storage in neural circuits. One means of achieving spatial specificity is to restrict signaling molecules to particular subcellular compartments using anchoring molecules such as A-Kinase Anchoring Proteins (AKAPs). Disruption of protein kinase A (PKA) anchoring to AKAPs impair...

Monte Carlo simulation, experiment, and continuum theory are used to examine the anchoring exhibited by a nematic liquid crystal at a patterned substrate comprising a periodic array of rectangles that, respectively, promote vertical and planar alignment. It is shown that the easy axis and effective anchoring energy promoted by such surfaces can be readily controlled by adjusting the design of t...

The anchoring of microtubules (MTs) to subcellular structures is critical for cell shape, polarity, and motility. In mammalian cells, the centrosome is a prominent MT anchoring structure. A number of proteins, including ninein, p150Glued, and EB1, have been implicated in centrosomal MT anchoring, but the process is far from understood. Here we show that CAP350 and FOP (FGFR1 oncogene partner) f...

Controlling charge transport through individual molecules and further understanding the effect of anchoring groups on charge transport are central themes in moleculebased devices. However, in most anchoring effect studies, only two, or at most three nonthiol anchoring groups were studied and compared for a specific system, i.e., using the same core structure. The scarcity of direct comparison d...

Current explanations for anchoring phenomena seem to be unable to account for the diversity of effects found by 40 years of research. Additionally, the theories do not have much to say about the processes that make anchors so resilient to modification. I argue that by focusing on the mechanisms involved in spatial representation, we can account for most anchoring effects which have spatial comp...

We propose a tensor description of surface anchoring of liquid crystals (LCs). The model allows one to consider both the homogeneous and inhomogeneous parts of LC anchoring and to calculate the cumulative effect of different treatments as a sum of corresponding tensors. For the planar alignment the tensor representation is reduced to the complex azimuthal anchoring coefficient, whose amplitude ...

Since the beginning of the twenty-first century, there has been widespread construction of submarine oil-gas transmission pipelines due to an increase in offshore oil exploration. Vessel anchoring operations are causing more damage to submarine pipelines due to shipping transportation also increasing. Therefore, it is essential that the influence of anchoring on the required burial depth of sub...

In situ photopolymerization of alkyl acrylate monomers in the presence of a nematic fluid provides a cellular matrix of liquid crystalline droplets in which the chemical structure of the encapsulating polymer exerts control over the alignment (anchoring) of the liquid crystalline molecules. Control is obtained by variation of the alkyl side chains and through copolymerization of two dissimilar ...

In previous anchoring studies people were asked to consider an anchor as a possible answer to the target question or were given informative anchors. The authors predicted that basic anchoring effects can occur, whereby uninformative numerical anchors influence a judgment even when people are not asked to compare this number to the target value. Five studies supported these hypotheses: Basic anc...

Providing information to test takers and test score users about the abilities of test takers at different score levels has been a persistent problem in educational and psychological measurement (Carroll, 1993). Scale anchoring (Beaton & Allen, 1992), a technique that describes what students at different points on a score scale know and can do, is a tool to provide such information. Scale anchor...