When reporting or using results of quantitative analysis, it is important to understand the uncertainties associated with the reported values. Every method, no matter how good, has limitations that create some degree of measurement error, which can be manifested as inaccuracy, imprecision, or a combination of these. Relative measurement error tends to increase as analyte concentrations decrease...

A biosensor can sense biological elements after interaction with the recognition element. The signal produced due to interaction of the analyte with its biochemical element is transduced by a transducer and detected by appropriate modes. The miniaturization of these biosensors at the nano level using nanostructures as a platform for sensing the analyte or its detection is called a nanobiosensor...

OF THE DISCLOSURE A method and device are provided for affinity gradient focusing for directing at least one analyte in a solution containing a pseudostationary phase and located in a conduit or microchannel. The method includes establishing a gradient in a retention factor of the pseudostationary phase for the at least one analyte. The analyte is caused to be moved within the conduit whereby t...

An exploration was made to develop a determination method of a low-concentration analyte by NIR spectroscopy. An absorber, silica gel was employed to extract and enrich a low-concentration analyte of ethyl carbamate. The solid absorber with the enriched analyte was measured by NIR spectroscopy in the range of 800 - 2500 nm. Afterwards, PLS regression was performed between the NIR spectra and th...

Most studies of analytical interference indicate the magnitude but not the type of interference. We developed a model for interference that assesses the magnitude of the following types of interference: independent of analyte concentration, dependent on analyte concentration, and a combination of the two. The experimental design for the model is an orthogonally arranged matrix with progressivel...

Density functional theory (DFT) simulations were used to determine the binding strength of 12 electron-donating analytes to the zinc metal center of a zinc phthalocyanine molecule (ZnPc monomer). The analyte binding strengths were compared to the analytes' enthalpies of complex formation with boron trifluoride (BF(3)), which is a direct measure of their electron donating ability or Lewis basici...

Several solvents and analyte protectants were evaluated for their ability to stabilize and maximize the recoveries of a number of organophosphorus pesticide residues during GC/MS analysis. Hexane provided the best analyte stability for a wide range of pesticides, and d-sorbitol offered the most benefit to recovery as an analyte protectant.

The advent of multiparameter technology has been driven by the need to understand the complexity in biological systems. It has spawned two main branches, one in the arena of high-content measurements, primarily in microscopy and flow cytometry where it has become commonplace to analyze multiple fluorescence signatures arising from multiple excitation sources and multiple emission wavelengths. M...