Aims Proximal renal tubular dysfunction (PRTD) is an infrequent complication after nucleotide analogue therapy. We evaluated the outcomes of PRTD and nephrotoxicity after nucleotide analogue withdrawal in chronic hepatitis B (CHB). Methods A longitudinal follow-up study was performed in patients with PRTD after nucleotide analogue discontinuation. Serum and urine were collected at baseline an...

This manual is only partially complete and is a work in progress. A completed manual will be available by January 1,2000. Cluster and TreeView are Y2K Compliant because they are oblivious of date and time.

OBJECTIVE To study the efficacy and safety of single intra-articular injection of 6-mL hylan G-F 20 in Chinese patients with symptomatic knee osteoarthritis. DESIGN Prospective case series. SETTING Six government hospitals in Hong Kong. PATIENTS Patients with primary knee osteoarthritis were recruited from six government hospitals from 1 October 2010 to 31 May 2012. All patients received ...

HENRY A. JOHNSON, 0000 MARK E. JOHNSON, 0000 DINCHEN A. KLEIN, 0000 LAURA A. KNABB, 0000 KIRK A. KREISEL, 0000 ARRON W. LAYTON, 0000 TIFFANY A. LEHANE, 0000 GREGORY D. LEWIS, 0000 JEFFREY M. LISAK, 0000 RONALD B. LOTT, JR., 0000 JAMES MATHES, 0000 TODD D. MOORE, 0000 JEFFREY A. NESHEIM, 0000 RICK L. NICKERSON, 0000 GREGORY J. OSTIDIEK, 0000 NANNETTE M. PACO, 0000 CHRISTOPHER F. POULIOT, 0000 JA...

In the terms of operational calculus the probability characteristics of direct and reverse residual renewal time of alternating renewal process, where renewal time depends on life-time, are found. 1. Definitions, Motivations and Formulation of the Problem 1.1 According to [1] let’s consider a system which fails after random life-time X1 and is fully renewed after the lapse of random time Y1. Th...

Despite the enormous media coverage that the issue of year 2000 (Y2K) readiness has received in recent months, the focus of that coverage has been restricted almost exclusively to technological aspects. Non-technical issues have tended to be either ignored completely or given very little attention. Most importantly, not much is known about the organisational processes of preparing to face this ...

I discuss the physics reach of a fixed-target charm experiment which can reconstruct >10 charm decays, three orders of magnitude beyond the largest extant sample. Such an experiment may run at Fermilab shortly after the Year 2000. In addition to “programmatic” charm physics such as spectroscopy, lifetimes, and tests of QCD, this “Charm2000” experiment will have significant sensitivity to new ph...

The Image Reduction and Analysis Facility is a scientific image processing package widely used throughout the astronomical community. IRAF has been developed and distributed by the National Optical Astronomy Observatory in Tucson, Arizona since the early 1980’s. Other observatories and projects have written many dozens of layered external application packages. More than ten thousand journal art...