The purpose of this thesis project is to develop an XTM (XML Topic Maps) wrapper, called XTMWrapper, for the functional and object-oriented DBMS Amos II so that XTM files can be accessed through Amos II using its query language, AmosQL. The wrapper can be used as a database loader for XTM files. The wrapper parses XTM files, translates them into an Amos II data representation, and populates the...

Section 1: Introduction .................................................................................................................... 2 1.1 About this Document/Prerequisites ....................................................................................... 2 1.2 Accessing AMOS ..............................................................................................................

The Tufted(1) (Tft(1)) dominant mutation promotes the generation of ectopic bristles (macrochaetae) in the dorsal mesothorax of Drosophila. Here we show that Tft(1) corresponds to a gain-of-function allele of the proneural gene amos that is associated with a chromosomal aberration at 36F-37A. This causes ectopic expression of amos in large domains of the lateral-dorsal embryonic ectoderm, which...

Using the well-characterised paradigm of Drosophila sensory nervous system development, we examine the functional distinctness of the Amos and Atonal (Ato) proneural transcription factors, which have different mutant phenotypes but share very high similarity in their signature bHLH domains. Using misexpression and mutant rescue assays, we show that Ato and Amos proteins have abundantly distinct...