In the reaction of m-aminophenol with carbohydrates in a thiourea/acetic acid reagent, addition of borate suppresses chromogen formation for hexoses and pentoses, and enhances it for disaccharides. All reaction products absorb maximally at 520 nm. The relatively greater intensity of the m-aminophenol/maltose reaction product was used in a saccharogenic method for amylase, with low blank reading...

The aims of this research are to synthesize and determine the formula, characteristics, complex structure Cu(II) Co(II) with 4-aminophenol investigate their antibacterial activity. complexes were synthesized by refluxing a solution CuSO4·5H2O CoSO4·7H2O, respectively, in methanol for 1 h. products characterized using UV-Vis spectroscopy, atomic absorption thermal analysis, conductivity, FTIR, m...

Sloane, Crane, and Mayer (2) reported that Mycobacterium smegmatis oxidizes aniline to p-aminophenol. It was also shown (2) that p-aminobenzoic acid (PABA) yields p-aminophenol after the PABA is first enzymatically decarboxylated to aniline. It is the purpose of this publication to present data on the effect of pH, citrate, inorganic ions, and inhibitors on this hydroxylation reaction. The data...

1. The metabolic effects of p-aminophenol have been compared with those of paracetamol and other analgesics in studies of rat liver and kidney in vitro. 2. p-Aminophenol injected into rats inhibited gluconeogenesis from lactate in renal cortical tubules, but not in isolated hepatocytes, and reduced kidney ATP content without affecting the ATP content of liver. Perfused kidneys from rats previou...

In spite of the variety of initial reactions, the aerobic biodegradation of aromatic compounds generally yields dihydroxy intermediates for ring cleavage. Recent investigation of the degradation of nitroaromatic compounds revealed that some nitroaromatic compounds are initially converted to 2-aminophenol rather than dihydroxy intermediates by a number of microorganisms. The complete pathway for...

A Pseudomonas pseudoalcaligenes able to use nitrobenzene as the sole source of carbon, nitrogen, and energy was isolated from soil and groundwater contaminated with nitrobenzene. The range of aromatic substrates able to support growth was limited to nitrobenzene, hydroxylaminobenzene, and 2-aminophenol. Washed suspensions of nitrobenzene-grown cells removed nitrobenzene from culture fluids with...

Copper(II) complexes containing two Schiff base ligands derived from 2-hydroxybenzaldehyde with 2-aminophenol and 3-aminophenol have been synthesized and characterized by means of analytical, magnetic, and spectroscopic methods. Bacteria, fungus, Entamoeba histolytica, and antineoplastic activities of the synthesized complexes have been determined by monitoring the parameters cell growth inhibi...

1. The glucuronide conjugation of p-nitrophenol, phenolphthalein, o-aminophenol and 4-methylumbelliferone by rat liver microsomes has been studied. The detergent Triton X-100 activated UDP-glucuronyltransferase activity towards all these substrates, therefore the optimum activating concentration was added in all experiments. 2. Mg(2+) enhanced the conjugation of the substrates. 3. With phenolph...

1. The purification to homogeneity of stable highly active preparations of UDP-glucuronyltransferase from liver of phenobarbital-treated rats is briefly described. 2. A single polypeptide was visible after sodium dodecyl sulphate/polyacrylamide-gel electrophoresis, of mol.wt.57000. 3. Antiserum raised against the pure enzyme produces a single sharp precipitin line after Ouchterlony double-diffu...

The structural properties of 4-substituted phenols capable of proton-coupled electron transfer (PCET) to superoxide (O2 ) were investigated on the basis of electrochemical and electron spin resonance (ESR) spectral measurements and supported by density functional theory calculations. Although the proton and electron donating abilities of phenols are considered to be important factors in PCET re...