Oxidative stress plays an important role in the progression of diabetes complications. The aim of the present study was to investigate the beneficial effect of oral administration of mangiferin in streptozotocin (STZ)-induced diabetic rats by measuring the oxidative indicators in liver and kidney as well as the ameliorative properties. Administration of mangiferin to diabetic rats significantly...

Hydrogen sulfide is a gasotransmitter with far-reaching effects on cell function. Studies show that, depending on the context, hydrogen sulfide can function as an ameliorative agent or as a mediator of kidney injury.

Rikkunshito (RKT), a Kampo medicine, has been reported to show an ameliorative effect on sustained hypophagia after novelty stress exposure in aged mice through serotonin 2C receptor (5-HT2CR) antagonism. We aimed to determine (1) whether the activation of anorexigenic neurons, corticotropin-releasing factor (CRF), and pro-opiomelanocortin (POMC) neurons, is involved in the initiation of hypoph...

The aim of the study was to investigate the ameliorative effects and the mechanism of action of L-2-oxothiazolidine-4-carboxylate (OTC) on acetaminophen (APAP)-induced hepatotoxicity in mice. Mice were randomly divided into six groups: normal control group, APAP only treated group, APAP + 25 mg/kg OTC, APAP + 50 mg/kg OTC, APAP + 100 mg/kg OTC, and APAP + 100 mg/kg N-acetylcysteine (NAC) as a r...

This paper investigates the role of humor in non-task oriented (topic restriction free) human-computer dialogue, as well as the correlation between humor and emotions elicited by it in users. A joke-telling conversational system, constructed for the needs of this research, was evaluated by the users as better and more human-like than a baseline system without humor. Automatic emotive evaluation...

Bromide and chloride are chemically related halide elements that the kidney works with to keep overall body content balanced. Also is a element known cause many neurotoxic other organs toxicity such as GIT tract, respiratory tract liver. Therefore, we aimed in present study on effect of bromide at daily intake doses investigate possible modulate its mechanism Ameliorative trail Sodium .Chloride...

OBJECTIVE To determine whether a goal-based system of advance planning, which allows patients to choose among five "pathways of care" (longevous, ameliorative/comprehensive, ameliorative/basic, palliative/comfort, or palliative/hospice), enables physicians to select treatment options in specified clinical situations. DESIGN A pencil and paper test was administered in which clinicians were pre...

Being a multifaceted unit idioms can be studied from five angles: meaning, function, style, emotiveness and contrastive analysis. The merit of this paper lies in the fact that it attempts to analyze evaluative functions English idioms. analysis is performed within functional framework thesis establish semantics Idioms operate as encoded resources for amplifying attitudinal meanings entities phe...