We have invented a mouse model of periodontitis associated with alveolar bone loss induced by lipopolysaccharide. Ovariectomized (OVX) animals are widely used as a model for osteoporosis due to estrogen deficiency. To define the relationship between periodontitis and osteoporosis, we examined the influence of estrogen deficiency on the mouse alveolar bone mass. In OVX mice, bone loss was detect...

Alveolar ridge resorption has long been considered an unavoidable consequence of tooth extraction. While the extent and pattern of resorption is variable among individuals, there is a progressive loss of ridge contour as a result of physiologic bone remodeling. Over the long term, prosthodontic complications, loss of function, and inadequate bone for the placement of dental implants may result....

PURPOSE The objective of this study was radiographic assessment of the premolar teeth abutments alveolar bone resorption in mandibular Kennedy Class I removable partial denture (RPD) utilizing the broad stress distribution philosophy, either designed with multiple circlet clasp or compound Aker clasp. MATERIALS AND METHODS Twelve patients were enrolled for this study with upper completely ede...

Periodontitis is a common chronic inflammatory disease, which leads to alveolar bone resorption. Healthy and functional alveolar bone, which can support the teeth and enable their movement, is very important for orthodontic treatment. Myricetin inhibited osteoclastogenesis by suppressing the expression of some genes, signaling pathways, and cytokines. This study aimed to investigate the effects...

Epigallocatechin gallate (EGCG), a major polyphenol in green tea, possesses antioxidant properties and regulates various cell functions. Here, we examined the function of EGCG in inflammatory bone resorption. In calvarial organ cultures, lipopolysaccharide (LPS)-induced bone resorption was clearly suppressed by EGCG. In osteoblasts, EGCG suppressed the LPS-induced expression of COX-2 and mPGES-...

background: socket preservation after tooth extraction is one of the indications of bone grafting to enhance preorthodontic condition. the aim of this study is to determine the effects of socket preservation on the immediate tooth movement, alveolar ridge height preservation and orthodontic root resorption. materials and methods: in a split-mouth technique, twelve sites in three dogs were inves...

(-)-Epigallocatechin-3-O-gallate (EGCG), present in green tea, exhibits antioxidant and antiallergy effects. EGCG3″Me, a 3-O-methylated derivative of EGCG, has been reported to show similar biological functions; the inhibitory activity of EGCG3″Me in a mouse allergy model was more potent than that of EGCG, probably due to the efficiency of absorption from the intestine. However, the functional ...

INTRODUCTION Vertical augmentation of the alveolar ridge is necessary for extensive resorption of the alveolar ridge. AIM To evaluate treatment outcome after alveolar ridge augmentation by a sandwich osteotomy combined with an interpositional allograft. PATIENTS AND METHODS The deficient alveolar ridges were augmented by a sandwich osteotomy combined with bovine collagen matrix as an interp...

objectives : bone assessment is essential for diagnosis, treatment planning and prediction of prognosis of periodontal diseases. however, two-dimensional radiographic techniques have multiple limitations, mainly addressed by the introduction of three-dimensional imaging techniques such as cone beam computed tomography (cbct). this study aimed to assess the accuracy of cbct for detection of marg...

The aim of this study was to compare the bone resorption differences between implant placement sites (IPS) and non-implant placement sites (NIPS) after autogenous block bone grafts in the anterior maxilla. Fourteen patients (58 edentulous sites) with alveolar atrophy in the anterior maxilla were treated with autogenous block bone grafts. CBCT examinations were performed at 1 month before surger...