A 61-year-old woman began to suffer bronchial asthma in 1985. She then developed low back pain and numbness along the lower extremities, eventually leading to bilateral drop foot in 1990. At that time, she was diagnosed as having lumbar disc hernia, and extirpation of the discs at the L3-4 and L4-5 was performed. However, her clinical condition showed little improvement. Six months later, she w...

Pulmonary involvement occurs in approximatively half of patients with allergic granulomatosis and angiitis (AGA). We studied bronchoalveolar cells from six patients with histologically proven AGA and compared our results with those obtained from four patients with chronic eosinophilic pneumonia (CEP), nine nonsmoking patients with bronchial asthma and blood eosinophilia, and 10 healthy nonsmoke...

1) Mazzantini M, Fattori B, Matteucci F, et al. Neuro-laryngeal involvement in Churg-Strauss syndrome. Eur Arch Otorhinolaryngol 1998;255:302-306. 2) Hueto-Perez-de-Heredia JJ, Dominguez-del-Valle FJ, Garcia E, et al. Chronic eosinophillic pneumonia as a presenting feature of Churg-Strauss syndrome. Eur Respir J 1994;7:1006-1008. 3) Cooper BJ, Bacal E, Patterson R. Allergic angiitis and granulo...

1. Takanashi T, Uchida S, Arita M, Okada M, Kashii S. Orbital inflammatory pseudotumor and ischaemic vasculitis in Churg-Strauss syndrome: report of two cases and review of the literature. Ophthalmology. 2001;108:1129-1133. 2. Masi AT, Hunder GG, Lie JT, et al. The American College of Rheumatology 1990 criteria for the classification of Churg-Strauss syndrome (allergic granulomatosis and angiit...

of Churg–Strauss vasculitis (CSV) is 2.5 per 100 000 people per year. It is characterized by pulmonary and systemic necrotizing vasculitis, vascular or extravascular granuloma, eosinophilia and tissue infiltration by eosinophils, and nonspecific elevation in the immunoglobulin E level. It is also found in those with asthma and allergic rhinitis or sinonasal polyposis. Coarse granular and perinu...

Pulmonary: asthma, pneumonitis and haemoptysis. Upper respiratory tract: allergic rhinitis, paranasal sinusitis, nasal polyposis. Cardiac involvement is common. [6]This includes heart failure, myocarditis and myocardial infarction. [7] Skin: purpura, skin nodules, leukocytoclastic angiitis with palpable purpura, livedo reticularis, urticaria, necrotic bullae and digital ischaemia. Renal: glomer...