To understand the effect of assortative mating on the genetic evolution of a population, we consider a finite population in which each individual has a type, determined by a sequence of n diallelic loci. We assume that the population evolves according to a Moran model with weak assortative mating, strong recombination and low mutation rates. With an appropriate rescaling of time, we obtain that...

background: north of iran is amongst high incidence rate areas of gastric carcinoma where environmental carcinogenic compounds especially agricultural pesticides are massively used. cytochrome p450 2e1 (cyp2e1) enzyme metabolically activates a large number of low molecular mass xenobiotics. the polymorphic nature of cyp2e1 gene control elements is associated with interindividual differences for...

Objectives: Polymorphisms in α-actinin-3 (ACTN3) gene are considered to be important in the genetic predisposition to human athletic performance. Most of the activities in soccer such as jumping, striking the ball, and running are considered plyometric and explosive. Performance power during such activities depends on the strength of the muscles involved. Therefore, high muscle strength i...

The spatial autocorrelation of allelic frequencies and geographical distances were studied at a natural population of Codium fragile in Korea. Within the C. fragile population, a strong spatial structure was observed for allozyme markers, indicating a very low amount of migration among subpopulations. The species showed a significant positive spatial autocorrelation as measured by Moran's I. Ge...

Without restricting the evolutionary forces that may be present, the theory of fixation indices, or F-statistics, in an arbitrarily subdivided population is developed systematically in terms of allelic and genotypic frequencies. The fixation indices for each homozygous genotype are expressed in terms of the fixation indices for the heterozygous genotypes. Therefore, together with the allelic fr...

Six Y chromosomal short tandem repeat (STR) loci, DYS19, DYS388, DYS390, DYS391, DYS392 and DYS393 were analysed in a reference group of Estonian population consisting of 107 unrelated Estonians. The primers and conditions for PCR amplification were chosen according to the literature references. Detection of alleles was performed by polyacrylamide gel electrophoresis, using silver staining for ...

Allelic and nonallelic (ectopic) recombination events were analyzed in a set of isogenic strains that carry marked Ty elements. We found that allelic recombination between Ty elements occurred at normal frequencies both in meiosis and mitosis. The marked Ty elements were involved in a large variety of different types of ectopic recombination and this variety was greater in mitosis than in meios...