OBJECTIVE After its first appearance in Alkhumra district of Jeddah in 1994-1995, and then in Makkah in 2001-2003, the new hemorrhagic fever virus, known as Alkhumra (misnamed as Alkhurma) virus (ALKV), has subsequently been reported from Najran, in the south border of Saudi Arabia. METHODS This is a descriptive cohort study summarizing the epidemiological, clinical, and laboratory characteri...

Human sera from Lodwar (77 sera), Nzoia (841 sera), Masinga (251 sera), Laisamis (174 sera) and the Malindi/Kilifi area (556 sera) in Kenya were tested by indirect immunofluorescence for antibodies against Marburg, Ebola (Zaire and Sudan strains), Congo haemorrhagic fever, Rift Valley fever and Lassa viruses. Antibodies against Ebola virus, particularly the Zaire strain, were detected in all re...

Orthobunyaviruses, tri-segmented, negative-sense RNA viruses, have long been associated with mild to severe human disease in Africa, but not haemorrhagic fever. However, during a Rift Valley fever outbreak in East Africa in 1997-1998, Ngari virus was isolated from two patients and antibody detected in several others with haemorrhagic fever. The isolates were used to identify Ngari virus as a na...

1. Grard G, Drexler JF, Fair J, Muyembe JJ, Wolfe ND, Drosten C, et al. Re-emergence of Crimean-Congo hemorrhagic fever virus in Central Africa. PLoS Negl Trop Dis. 2011;5:e1350. http://dx.doi. org/10.1371/journal.pntd.0001350 2. Mild M, Simon M, Albert J, Mirazimi A. Towards an understanding of the migration of Crimean-Congo hemorrhagic fever virus. J Gen Virol. 2010;91:199–207. http://dx.doi....

....................................................................................................... xiii Sammanfattning på svenska .......................................................................... xv Case report* .................................................................................................... 1 Part 1 – Infectious diseases and pregnancy ............................

identity to the prototype strain. Alzahrani et al. [2] quote the paper by Zaki [5] . From this paper, however, it is not possible to obtain information on where the index patient came from. While both names can probably be justified, it should be the discoverer who has the right to name a virus. The debate should come to an end once the ICTV has made its statement. Another issue is that apparen...

Viral haemorrhagic fevers (VHF) caused by arenaviruses are among the most devastating emerging human diseases. The most important pathogen among the arenaviruses is Lassa virus (LASV), the causative agent of Lassa fever that is endemic to West Africa. On the South American continent, the New World arenavirus Junin virus (JUNV), Machupo (MACV), Guanarito (GTOV), and Sabia virus (SABV) have emerg...

The aim of this communication is to provide preliminary information on the tick-borne pathogens of potential zoonotic importance present in southern Africa, mainly focusing on their geographical distribution and host range, and to identify research gaps. The following tick-borne zoonoses have been reported to occur in southern Africa based mainly on case reports: Crimean-Congo haemorrhagic feve...

368 www.thelancet.com/infection Vol 17 April 2017 1 Haider S, Hassali AM, Iqbal Q, et al. Crimean-Congo haemorrhagic fever in Pakistan. Lancet Infect Dis 2016; 16: 1333. 2 Müller MA, Devignot S, Lattwein E, et al. Evidence for widespread infection of African bats with Crimean-Congo hemorrhagic fever-like viruses. Sci Rep 2016; 6: 26637. 3 Mourya DT, Yadav PD, Shete AM, et al. Cross-sectional se...