In an "aldol addition" reaction an enol or enolate of an aldehyde or ketone reacts with a second aldehyde or ketone forming a new carbon-carbon bond which makes the aldol reaction an important reaction for organic synthesis. Originally, the aldol reaction used ethanal (see below) and therefore the product contained both an aldehyde and an alcohol functional group; thus it became known as the al...

In an "aldol addition" reaction an enol or enolate of an aldehyde or ketone reacts with a second aldehyde or ketone forming a new carbon-carbon bond. This makes the aldol reaction an important reaction for organic synthesis. Originally, the aldol reaction used ethanal (see below) and therefore the product contained both an aldehyde and an alcohol functional group; thus it became known as the al...

Although aldol condensation is one of the most important organic reactions, capable of forming new C-C bonds, its mechanism has never been fully established. We now conclude that the rate-limiting step in the base-catalyzed aldol condensation of benzaldehydes with acetophenones, to produce chalcones, is the final loss of hydroxide and formation of the C═C bond. This conclusion is based on a stu...

2-ethylhexanal is synthesized directly from crotonaldehyde over a bifunctional acidic resin-supported palladium catalyst via hydrogenation and aldol condensation in supercritical CO2.

Potassium modified acid–base bifunctionalized MgAl-SBA-15 for mild aldol condensation of furfural and acetone to high-quality jet-fuel range or chemical intermediates.

Particles in the upper troposphere and lower stratosphere (UT/LS) consist mostly of concentrated sulfuric acid (40-80 wt %) in water. However, airborne measurements have shown that these particles also contain a significant fraction of organic compounds of unknown chemical composition. Acid-catalyzed reactions of carbonyl species are believed to be responsible for significant transfer of gas ph...

2,2,2-Trichloro-1-aryl-ethanones can be reduced by RMgX to the corresponding 2,2-dichloro-1-arylethen-1-olates and trapped with a range of electrophiles resulting in either reduction, reduction/aldol, reduction/Claisen condensation or reduction/aldol-Tishchenko products. In addition we demonstrate that 2,2-dichloro-1-arylethen-1-olates undergo counter-ion controlled Darzens condensations, which...