PURPOSES To evaluate quantitative air trapping measurements in children with mild cystic fibrosis (CF) lung disease during a 1-year, double-blind, placebo-controlled, recombinant human deoxyribonuclease (rhDNase) [dornase alfa] intervention trial and compare results from quantitative air trapping with those from spirometry or visually scored high-resolution CT (HRCT) scans of the chest. MATER...

PURPOSE To automatically derive the degree of air trapping in mild cystic fibrosis (CF) disease from high-resolution CT (HRCT) data, and to evaluate the discriminating power of the measurement. MATERIALS AND METHODS The data consist of six pairs of anatomically matched tomographic slices, obtained during breath-holding in triggered HRCT acquisitions. The pairs consist of an inspiratory slice,...

Purpose: To investigate important factors affecting the frequency of air trapping through observation of normal lung attenuation, and propose a cause of heterogeneous attenuation. Materials and Methods: In this ethical committee-approved study, a total of 109 patients (30 males, 79 females; mean age, 58.2 years; range, 27 81 years) were included. All patients had undergone inspiratory and expir...

Objective: To evaluate the utility of inspiratory capacity (IC) measured by simple spirometry as an indirect measure of air trapping. Method: Functional residual capacity (FRC) and IC were determined, respectively, by a body plethysmography and by spirometry. Air trapping was defi ned by a FRC higher than 120%. Spearman’s rho between IC and FRC is determined and the receiver operating character...

Dr.Mirsadraei and colleagues performed an interesting study about the lung HRCT findings in chemical warfare patients who suffering from long-term pulmonary complications. They found that air trapping and mosaic attenuation were the most common lung HRCT findings. Also they divided patients in different clinical entities according to the lung HRCT findings (Bronchiolitis Oblitrans, pulmonary fi...

OBJECTIVE The purpose of this study was to compare air trapping in healthy volunteers with asthmatics using pulmonary function test and quantitative data, such as specific volume change from paired inspiratory CT and registered expiratory CT. MATERIALS AND METHODS Sixteen healthy volunteers and 9 asthmatics underwent paired inspiratory/expiratory CT. ΔSV, which represents the ratio of air fra...

High-resolution computed tomography (HRCT) may be useful to monitor lung disease in children with common variable immunodeficiency disorder (CVID). We evaluated interobserver agreement and correlation with pulmonary function tests (PFTs) for automated quantification and visual scoring of air trapping and airway wall thickening on HRCT in paediatric CVID patients. In a cohort of 51 children with...

In this paper we show that laser beams containing phase singularity can be used for trapping and guiding light-absorbing particles in air. The experiments were performed with agglomerates of carbon nanoparticles with the size in the range 0.1–10 μm; the typical cw laser power was of a few mW. The stability of open-air three-dimensional trapping was within ±2 μm in both the transverse and the lo...

OBJECTIVE We describe the application of an optical flow method to inspiratory and expiratory high-resolution volumetric lung MDCT for the assessment of regional air trapping. CONCLUSION Qualitative and quantitative assessment of regional air trapping is feasible using an optical flow method to align volumetric MDCT data sets.