A new antiherpetic agent, AH-758, was isolated from the culture broth of Streptomyces sp. strain No. 758. The structure was determined by NMR special analyses to be a new antibiotic belonging to bafilomycin group containing (5-oxo-2-pyrrolin-2-yl) methyl fumarate in its C-21.

Let φ(x1, . . . , xh, y) = u1x1 + · · · + uhxh + vy be a linear form with nonzero integer coefficients u1, . . . , uh, v. Let A = (A1, . . . , Ah) be an h-tuple of finite sets of integers and let B be an infinite set of integers. Define the representation function associated to the form φ and the sets A and B as follows: R (φ) A,B (n) = card ({(a1, . . . , ah, b) ∈ A1 × · · · × Ah × B : φ(a1, ....

AIM The purpose of this study was to determine whether AH 26 and AH Plus have in vitro oestrogenic effects. METHODOLOGY MCF-7 breast cancer cells were trypsinized and plated in 24-well plates at initial concentrations of 10,000 cells per well in 5% FBS in DME. Cells were allowed to attach for 24 h; then the seeding medium was replaced with 10% CDHuS-supplemented phenol red-free DME. Different...

Memon, Riaz A., John Fuller, Arthur H. Moser, Kenneth R. Feingold, and Carl Grunfeld. In vivo regulation of plasma platelet-activating factor acetylhydrolase during the acute phase response. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R94–R103, 1999.—Plasma plateletactivating factor acetylhydrolase (PAF-AH) hydrolyzes PAF and oxidized phospholipids and is associated with lip...

BACKGROUND Advanced puberty in girls is defined as the onset of puberty between the ages of 8 yr and 10 yr. The objective was to predict adult height (AH) at initial evaluation and to characterize patients with an actual AH below -2 SD (152 cm) and/or lower than their target height (TH) by > one SD (5.6 cm). METHODS Data analysis using multiple linear regression models was performed in 50 gir...