نتایج جستجو برای: agonist 5
تعداد نتایج: 1253596 فیلتر نتایج به سال:
Nearly 30 years have passed since the first selective 5-HT1 receptor agonist sumatriptan became a choice of treatment for migraineurs. Recently, new class antimigraine drugs has joined antimig...
Background: Toll like receptors play a major role in immune responses against Leishmania parasites. Objective: To evaluate the efficacy of vaccination with live attenuated L. major and TLR4 agonist in protection against L. major infection. Methods: Attenuated L. major was prepared by continuous sub-culturing of the parasite. A total of 90 mice were assigned to 9 groups including 6 groups of BAL...
Rationale: The ? 2 -adrenoceptor (? -AR), a prototypical GPCR (G protein-coupled receptor), couples to both G s and i proteins. Stimulation of the -AR is beneficial humans animals with heart failure presumably because it activates downstream -PI3K-Akt cell survival pathway. Cardiac signaling can be regulated by crosstalk or heterodimerization other GPCRs, but physiological pathophysiological si...
growing evidence suggests that serotonin plays an important role in learning and memory and all its receptors might be implicated in this process. the present study aimed at investigating and comparing the possible involvement of 5-ht 3 and 5-ht 4 receptor (r) agonists/antagonists upon consolidation of inhibitory avoidance memory in the pre-limbic (pl) area. bilateral intra-pl microinjections o...
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