in this paper, differences in porosity, compressive strength and tablet- forming ability of carbamazepine crystals agglomerated under similar condition, but subjected to different drying temperatures are reported. the agglomerates were prepared by spherical crystallization method and thereafter dried without agitation at different temperature. an increased drying temperature did not affect the ...

Spherically agglomerated solid dispersions of carvedilol (CAR) were prepared with polyvinyl-pyrrolidone (PVP) using acetone, water and dichloromethane as solvent, non-solvent and bridging liquid, respectively. The prepared agglomerates were evaluated for its percentage yield, drug content, morphology, thermal behavior, micromeritic properties, aqueous solubility and in vitro drug release. Diffe...

Dust particles generated in low temperature plasmas as used for microelectronics fabrication are often agglomerates of smaller monodisperse particles. The transport of these agglomerates, and the subsequent contamination of surfaces, depends on the details of ion-momentum transfer ~ion drag! to, and electrostatic forces on, the agglomerate. Given that the charge distribution on the surface of t...

Rutile titania powders were synthesized via a sol-gel/hydrothermal process using nitric acid as the catalyst. A molar acid to alkoxide ratio of 10 and a water to alkoxide molar ratio of 250 produced 100% rutile powders when precipitated below 45 °C. Higher temperatures yielded initially either anatase or mixtures of anatase and rutile. Spherulitic growth produced cauliflower-shaped agglomerates...

Objective(s):This study dealt with the wet agglomeration process in which a small quantity of binder liquid was added into a suspension of crystals, directly in the stirring vessel where the crystallization took place. The purpose of this investigation was evaluation of the effect of temperature on the agglomeration process in order to gain insight into the mechanism of the formation of the agg...

The aim of present study was to prepare and characterize the recrystallized agglomerates of water insoluble non steroidal anti-inflammatory drug, indomethacin (IM) with hydrophilic polymers like polyvinyl pyrrolidone (PVP),hydroxyl ethyl cellulose (HEC) and hydroxyl propyl methyl cellulose (HPMC) by using emulsion solvent diffusion (ESD) technique for enhancing the solubility, dissolution rate,...

objective(s) ibuprofen is a problematic drug in tableting, and dissolution due to its poor solubility, hydrophobicity, and tendency to stick to surface. because of the bad compaction behavior ibuprofen has to be granulated usually before tableting. however, it would be more satisfactory to obtain directly during the crystallization step crystalline particles that can be directly compressed and ...

Yttria-doped zirconia powders" with an extremely small crystallite size (8 nm) and a narrow size distribution have been prepared by gel precipitation methods. Precipitation of an alkoxide solution in water ("alkoxide" synthesis) results in weaker agglomerates when compared with a precipitation of a metal chloride solution in ammonia ("chloride" synthesis). Both types of agglomerate are fracture...

The dispersion of carbon black agglomerates suspended in polydimethyl siloxane (PDMS) or polybutadiene (PBD) liquids has been studied. Agglomerates comprised of either a low-structure or a high-structure carbonblack were subjected to simple shear flow. Two characteristic length scales that affect the dispersion process are identified. One length scale (Lp) is a measure of the ease with which fl...