In the present study, possible cytochrome enzyme inhibition potential of Aegle marmelos (L.) Corrêa fruit and its bioactive compound was evaluated. Interaction potential of Aegle marmelos extract was evaluated through CYP450carbonmonoxide complex (CYP450-CO) assay. Additionally, influence on individual major human cytochrome P450 drug metabolizing enzymes such as CYP3A4, CYP2D6, CYP2C9 and CYP1...

Aegle marmelos is a medicinal plant commonly known as bale. This plant contains different components of therapeutic value. The ethanolic extract of Aegle marmelos showed the presence of phytoconstituents like flavonoids, triterpenoids, coumarins, sterols, triterpenoids, alkaloids with other constituents. In present investigation, antibacterial, antifungal and wound healing effects of ethanolic ...

Oxidative stress induced by alloxan has been shown to damage pancreatic beta-cell and produce hyperglycemia in rats. Aegle marmelos leaf extract is being used in Ayurveda as a medicine for diabetes. The present study examined the action of Aegle marmelos against experimental diabetes as well as the antioxidant potential of the drug. A methanolic extract of Aegle marmelos was found to reduce blo...

The present study was carried out to screen and evaluate the antimicrobial activity of leaf extracts from Aegle marmelos (L.) Corr. Petroleum ether, Dichloromethane, Chloroform, Ethanol and Aqueous extract of the leaves were tested against selected Gram positive and Gram negative bacteria. Results depict that phytochemical extracts of A. marmelos exhibited significant anti-bacterial activity. H...

In the present study, methanolic extracts of roots of Vitex negundo L. and extracts of leaves of Vitex negundo L., Ricinus communis L. and Aegle marmelos Corr. were explored for possible antifilarial effect against Brugia malayi microfilariae. It was observed that among the herbal extracts, root extract of Vitex negundo L. and leaves extract of Aegle marmelos Corr. at 100 ng/ml concentration sh...

The antibacterial activity of the methanol, chloroform and aqueous extracts from the leaves, bark and fruit of A. marmelos was studied using disc diffusion method against Bacillus subtilis, Staphylococcus aureus (Gram Positive), Klebsiella pneumoniae, Proteus mirabilis, Escherichia coli, Salmonella paratyphi A and Salmonella paratyphi B (Gram Negative). Results suggest that the methanolic extra...

Myocardial infarction is a major public health concern and the leading cause of death throughout the world. The present study investigates the ability of Aegle marmelos fruit extract to prevent pathological changes and oxidative stress after isoproterenol induced myocardial infarction in rats. In vitro studies showed that Aegle marmelos fruit extract possesses antioxidant activity. Administrati...

In this study ethanolic extract of Aegle marmelos was evaluated for its anti-ulcer activity against aspirininduced gastric ulcer in albino rats. Various biochemical parameters such as gastric volume, pH of gastric content, free acidity and total acidity, total carbohydrate content such as total protein, hexoses, hexosamine, fucose and sialic acid were estimated in alcoholic precipitate of gastr...

The aim of this study is to evaluate anti-inflammatory activity and to determine phytochemical constituent of ethanolic leaf extract of Aegle marmelos(L.) Corr. Serr.. Plant materials are collected from Punjab. Ethanolic extract was screened for different phytochemical constituents. Acute toxicity studies are done according to OECD guidelines. Ethanolic extracts were screened for anti-inflammat...

The objective of this study was to investigate the efficacy of Nelumbo nucifera and Aegle marmelos on common carp exposed to sub-lethal concentrations of combined heavy metals (5 ppm) under laboratory conditions. The fish were treated with Nelumbo nucifera (500 mg/kg bwt) and Aegle marmelos (500 mg/kgbwt) for 30 days as a dietary supplement. The blood biochemical parameters of the fish were eva...