We describe an algorithm that explores potential energy surfaces (PES) and finds approximate reaction paths and transition states. A few (≈6) evolving atomic configurations ("climbers") start near a local minimum M1 of the PES. The climbers seek a shallow ascent, low energy, path toward a saddle point S12, cross over to another valley of the PES, and climb down to a new minimum M2 that was not ...

PURPOSE Cisplatin based concomitant chemoradiation (CRT) is the standard treatment for locally advanced cervical cancer (CC). Glutathione S-transferase (GST), a phase II antioxidant enzyme is induced by oxidative stress generated by drugs and reactive oxidants. The present study was undertaken to evaluate the association of GSTM1, T1 and P1 polymorphisms with the outcome of CRT treatment in CC ...

BACKGROUND AND AIM The prevalence of gastric cancer and Helicobacter pylori infection is unacceptably high in Korea. This study was performed to evaluate the prevalence of atrophic gastritis (AG) and intestinal metaplasia (IM) and to identify their risk factors with respect to H. pylori virulence factors, and environmental and host factors, in Korean population without significant gastroduodena...

In clinical practice, the effectiveness of the rehabilitation therapy such as acupuncture combining conventional Western medicine (AG) on stroke people's motor-related brain network and their behaviors has not been systematically studied. In the present study, seventeen adult ischemic patients were collected and divided into two groups: the conventional Western medicine treatment group (CG) and...

Controlled ON/OFF stereocomplexation of dynamic helical polymer-metal nanoparticle nanocomposites─poly(phenylacetylene)-MNP nanocomposites (M = Au or Ag)─is presented. These novel hybrid materials can be found either as well-dispersed metal nanoparticles (MNPs) (stereocomplex OFF) fiber-like aggregates ON) with the distributed along material. A stereocomplex-MNP nanocomposite is formed by inter...

in the present survey 194 gram positive bacteria isolated from the rhizosphere of bean from markazi province and also 41 isolates from the collection of research center of biological control at tehran universitiy were evaluated on the basis of inhibitionry zone of fungal growth. finally eight more appropriate strains of b. subtilis were selected for greenhouse trials. results indicated that ant...

We combined bifocal transcranial magnetic stimulation (TMS) and diffusion tensor imaging (DTI) tractography to investigate in humans the contribution of connections originating from different parietal areas in planning of different reaching to grasp movements. TMS experiments revealed that in the left hemisphere functional connectivity between the primary motor cortex (M1) and a portion of the ...

The human HLA-A2-restricted CD8(+) T cell response to influenza A virus (IAV) is largely directed against the matrix protein-derived M1(58-66) epitope and represents an archetypal example of CD8(+) T cell immunodominance. In this study, we examined the CD8(+) T cell hierarchy to M1(58-66) and two subdominant IAV-specific epitopes: NS1(122-130) and PA(46-55) in HLA-A2(+) human subjects and HLA-A...

Herein, we report a simple and scalable synthesis route to prepare Ag-functionalized porous ZnO sheets their enhanced NO2 gas sensing properties. Porous functionalized with well-dispersed submicron Ag particles were prepared by using hydrothermal method-based one-pot from Zn precursors. performance (response, selectivity, response time, recovery time) was optimized at 200°C in the sensor fabric...