HIGH RISK GENOTYPES AMONG IRANIAN HEALTHY WOMEN: A SYSTEMATIC REVIEW AND META-ANALYSIS Mina Malary, Mahmood Moosazadeh, Zeinab Hamzehgardeshi, Mahdi Afshari, Iman Moghaddasifar, Amin Afsharimoghadam. Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran; Assistant Professor, Health Sciences Research Center, Faculty of Health, Mazandaran University of Medical Sciences...

Since 1980, when the idea of drug-delivery was proposed, various drug-carriers have been developed, including DNA, proteins, liposomes and several other polymer cages, consisting of many well established natural and synthetic nano-particles. All these drug-carriers can self-assemble in the body and can be manipulated for safer delivery into target tissues. By definition, nano-scale drug deliver...

Paper III Nørskov AK, Lundstrøm LH, Rosenstock CV, Wetterslev J. Detailed statistical analysis plan for the difficult airway management (DIFFICAIR) trial. Trials 2014, 15:173. Paper IV Nørskov AK, Wetterslev J, Rosenstock CV, Afshari A, Astrup G, Jakobsen JC, the DIFFICAIR trial author group, Lundstrøm LH. Effects of using the Simplified Airway Risk Index versus usual airway assessment on unant...

The ToxChip, a DNA microarray chip, allows the monitoring of the expression levels of thousands of different genes at a time, thereby condensing months of painstaking laboratory tasks into a day's work. For toxicology researchers in particular, this tool is important because it promises a more effective way to identify environmental hazards and their effects on DNA. The ToxChip, developed by NI...

The fecundity in sheep has been much interested for producers due to its economical importance. Growth differentiation factor 9 (GDF9) is an autosomal gene with over dominance effect for twosingle nucleotide polymorphisms(SNPs), which resulted in sterility in homozygote mutant ewes and additive effect for three SNPs, without showing sterility event. In the present study, DNA was extracted from ...

the genetic parameters and (co) variance components of body weight at birth (bw), weaning (ww) and six months of age (bw6) and average daily gain (adg) pre and post-weaning of afshari sheep were estimated using restricted maximum likelihood (reml) methodology and animal model implemented in dfreml software. the likelihood ratio test (lrt) was used to compare the models. year of birth, age of mo...

this study investigated the effect of dietary supplementation with calcium salts of fatty acids using 48 afshari ewes randomly allocated to four treatments. all groups used in flushing period and only the source of energy were different between rations. the ewes were divided into four groups: a-barely grain; group b-received 5% of csfa with source of flaxseed oil (w3); group c-received 5% of cs...

Recently Afshari et al. reported on the detection of a new infrared band which was assigned to the "long-anticipated polar isomer of the OCS dimer" [J. Chem. Phys. 126, 071102 (2007)]. The authors report here the microwave confirmation of their results. The lowest energy, nonpolar isomer of (OCS)2 has long been known from IR spectroscopy, while the polar form has only been deduced from qualitat...

Calpastatin is an endogenous inhibitor of calpain (calcium-dependent cysteine protease). Calpastatin activityis highly related to the rate of protein turnover and rate of meat tenderization. In order to characterize thestructure of calpastatin in Iranian Afshari breed of sheep, intron 6 and partial exon 7 of the L domain wereamplified and sequenced. A fragment of approximately...