Introduction: Glucocorticoids are considered the cornerstone of the induction phase in all treatment protocols of acute lymphoblastic leukemia (ALL). Among the adverse effects of high-dose glucocorticoid treatment, adrenal insufficiency is secondary to suppression of the hypothalamic-pituitary-adrenal (HPA) axis. This drawback of exogenous steroid therapy gains a contemporary particular relevan...

introduction: coronary angiography and angioplasty procedures lead to significant radiation exposure of patients. in the current study, the average radiation dose to patients during angiography in the angiography department of shahid-madani hospital was determined. materials and methods: an image intensifier based angiography unit (philips bh 3000) was used for angiography procedures. the accur...

introduction: in 2000, the unscear reported that ct constitutes 5% of all the medical x-ray  examinations and it contributes 34% of the resultant collective dose worldwide. children are more  sensitive to the ionizing radiations than adults. so, routine quality control tests are expected to be  carried out periodically on the ct scanners. the aim of this research was to estimate the effective  ...

Prednisolone and adrenocorticotropic hormone (ACTH) are "hormone" therapies for infantile spasms. There is limited data on the occurrence of decreased adrenal reserve or signs of clinical adrenal insufficiency after hormone therapy. This is a retrospective medical record review of patients referred to our Infantile Spasms Program. Our standardized infantile spasms management guideline began in ...

background: although ionizing radiation is widely used to diagnose many diseases, the relevant hazards are known to be as an important limitation of its application. it is believed that the awareness of ionizing radiation dose values is one of the main stages in patient's radiation protection. the purpose of this study has been to investigate the level of physicians' knowledge about r...

Cushing's syndrome is a pathological condition where surgery may be lifesaving. The proper diagnosis depends upon the hormonal pattern of the patient, various dynamic tests and imagistic investigations. We report a case of a patient with Cushing's syndrome, with bilateral adrenal tumors and a pituitary microadenoma. She presented increased levels of basal cortisol, unsuppressed during a low and...

background: the number of interventional cardiology (ic) procedures has increased rapidly. coronary angiography (ca) and percutaneous transluminal coronary angioplasty (ptca) are now widely performed as a matter of routine, and they are considered safe procedures for experienced cardiologists. however, it is also known that these procedures are associated with high radiation doses due to long f...

Adrenal crisis is a life-threatening emergency contributing to the excess mortality of patients with adrenal insufficiency. Studies in patients on chronic replacement therapy for adrenal insufficiency have revealed an incidence of 5-10 adrenal crises/100 patient years and suggested a mortality rate from adrenal crisis of 0.5/100 patient years. Patients with adrenal crisis typically present with...