Recent advances in molecular force measurements have resulted in the quantification of the nanomechanical properties of single molecular bonds, and elucidated novel relationships between molecular architecture and biomolecular adhesion. The measured forces to rupture single intermolecular bonds revealed novel and unexpected ways that proteins respond to mechanical force. Measurement of the magn...

Abstract We study adhesion of the gluten proteins during shear and normal deformations as described by a coarse-grained molecular dynamics. show that two types deformation have different impact on proteins. also calculate dynamic modulus critical strain find results to be consistent with slip-bond theory which assumes can treated an interconnected network polymers. Graphical

background : rhoptries are unique secretory/excretory organelles that are found exclusively in the apicomplexa, and their contents are discharged at the time of invasion and are critical in the establishment of productive infection. several rhoptry proteins have been identified in toxoplasma gondii , plasmodium falciparum and neospora caninum and have been linked not only with the parasites’ ad...

The physiologic function of the immune system is defense against infectious microbes and internal tumour cells, Therefore, need to have precise modulatory mechanisms to maintain the body homeostasis. The mammalian cellular CD200 (OX2)/CD200R interaction is one of such modulatory mechanisms in which myeloid and lymphoid cells are regulated. CD200 and CD200R molecules are membrane proteins that t...

In this work, a slippery liquid-infused silver-polytetrafluoroethylene (AgFP) coating was fabricated via spontaneous polycondensation of 1H,1H,2H,2H-perfluorooctyltriethoxysilane (PFOTES) onto an electroless AgF sublayer. The AgFP demonstrated great stability and superior repellence against liquids with wide range surface tensions. anti-biofouling properties were investigated by adsorption Esch...

Cell adhesion to the extracellular matrix is important in many biological processes. Various ligands and cell surface receptors have been defined. In vitro cell adhesion to matrix proteins and to other 'adhesion' proteins is generally measured on plastic culture substrates. We have found that the presence of low levels of adhesion proteins, e.g. fibronectin, together with high concentrations of...

Proteins are important in bacterial adhesion, but interactions at molecular-scales between proteins and specific functional groups are not well understood. The adhesion forces between four proteins [bovine serum albumin (BSA), protein A, lysozyme, and poly-d-lysine] and COOH, NH2 and OH-functionalized (latex) colloids were examined using colloid probe atomic force microscopy (AFM) as the functi...

Cell adhesion is tightly controlled in multicellular organisms, for example, through proteolytic ectodomain shedding of the adhesion-mediating cell surface transmembrane proteins. In brain, proteins required nervous system development and function, but only a few has been studied detail mammalian brain. One such protein endoglycan (PODXL2), which belongs to CD34-family highly glycosylated sialo...

the physiologic function of the immune system is defense against infectious microbes and internal tumour cells, therefore, need to have precise modulatory mechanisms to maintain the body homeostasis. the mammalian cellular cd200 (ox2)/cd200r interaction is one of such modulatory mechanisms in which myeloid and lymphoid cells are regulated. cd200 and cd200r molecules are membrane proteins that t...