background : adenomyosis is a common benign disorder in premenopausal women. it may be presents with uterus enlargement, pelvic pain, abnormal uterine bleeding and dysmenorrheal. the main objective of this study was to assess prior uterine surgery was a risk factor for adenomyosis. materials and methods: in this cross-sectional study, we reviewed the medical records of all women who underwent h...

Until recently, adenomyosis has been associated with multiparity, not impaired fertility. Currently, adenomyosis is diagnosed with increasing frequency in infertile patients since women delay their first pregnancy until their late 30s or early 40s. Although an association between adenomyosis and infertility has not been fully established, based on the available information, recent studies sugge...

STUDY QUESTION Is the presence of adenomyosis associated with menorrhagia? SUMMARY ANSWER There was no significant association between adenomyosis and menorrhagia, but there was a significant positive correlation between the severity of adenomyosis on ultrasound and the amount of menstrual loss estimated using pictorial blood loss assessment charts. WHAT IS KNOWN ALREADY There is no consens...

Evidence has been provided that pelvic endometriosis is significantly associated with uterine adenomyosis and that the latter constitutes the major factor of infertility in such conditions. Furthermore, it has become evident that both adenomyosis and endometriosis constitute a pathophysiological and nosological entity. Mild peritoneal endometriosis of the fertile woman and premenopausal adenomy...

CA 125 Adenomyosis Immunohistochemistry Abstract To investigate the histogenic and cytogenic localization of CA 125 in patients with adenomyosis, sections from 8 adenomyosis cases were expressed with monoclonal anti-CA 125 antibodies. Consequently, CA 125 proved to be present on the glandular epithelium localized in muscle layers of adenomyosis. S. Kijima, Department of Obstetrics and Gynecolog...

Abnormal endometrial expression of CC-chemokine receptor-1 (CCR1) may play a role in the pathogenesis of endometriosis. Adenomyosis, also called endometriosis interna, occurs when the endometrium invades the myometrium. The objective of this study was to determine CCR1 expression in endometrium in women with adenomyosis as compared to women without adenomyosis. We evaluated endometrial mRNA and...

AIMS This study is to investigate the expression levels of vascular endothelial growth factor (VEGF) and cancer antigen 125 (CA125) in serum of adenomyosis patients before and after interventional therapy. The role of serum levels of VEGF and CA125 for the prognosis of adenomyosis is further studied. METHODS A total of 80 adenomyosis patients treated with interventional therapy and 40 healthy...

Purpose To investigate the impact of adenomyosis on the complications and outcomes of pregnancy in Japan. Methods We carried out a multicenter retrospective questionnaire survey. A questionnaire regarding pregnancy complications and the outcomes of pregnancy was sent to 725 facilities. Results Data were obtained on the cases of 272 pregnant women with adenomyosis from 65 facilities. The com...

Adenomyosis is defined as the presence of glandular foci beside the endometrium of uterus: in the myometrium and/or perimetrium depending on the progress of the disorder. So far, adenomyosis has been diagnosed in women and rodents, and studies conducted on cows have been rare. In this review we: (1) summarize the knowledge regarding adenomyosis, (2) compare the symptoms and aetiopathology betwe...

The incidence of cancer from adenomyosis is rare. Previously, only two cases of clear cell adenocarcinoma (CCA) arising from adenomyosis have been reported in English literature. Here, we report a case of CCA arising from adenomyosis. A 52-year-old postmenopausal Korean woman presented with complaints of vaginal bleeding and back pain. Endometrial biopsy revealed endometrial polyp with atrophic...