Drugs of abuse are rewarding to addicted and nonaddicted subjects, but they trigger craving and compulsive intake only in addicted subjects. Here, we used positron emission tomography (PET) and [18F] deoxyglucose to compare the brain metabolic responses (marker of brain function) of cocaine-addicted subjects (n = 21) and controls (n = 15) to identify brain regions that are uniquely activated in...

BACKGROUND Previous studies on Internet addiction point towards a particular constellation of personality traits and deficits in social competence of players addicted to massively multiplayer online role-playing games (MMORPGs), which are hypothesized to result from impairments in self-concept. The aim of this study was to examine differences in self-concept and degree of avatar identification ...

The small heat-shock protein of 27 kDa (HSP27) is highly expressed in many cancers and is associated with aggressive tumour behaviour, metastasis, poor prognosis and resistance to chemotherapy. We aimed at assessing the role of HSP27 in modulating responses to target therapies. We selected several oncogene-addicted cancer cell lines, which undergo either cell cycle blockade or cell death in res...

BACKGROUND Chronic opioid treatment in animal models has shown to alter hematological parameters. OBJECTIVES The aim of this study was to evaluate the biological effects of opium on the number of peripheral blood cells and red blood cells (RBCs) indices in diabetic rats. MATERIALS AND METHODS Peripheral blood samples were collected from diabetic, opium-addicted, diabetic opium-addicted and ...

BACKGROUND Family functioning is considered to have a significant impact on the beginnings and maintenance of substance use. OBJECTIVES The main purpose of this study was to examine and compare the dimensions of family functioning among addicted and non-addicted individuals. PATIENTS AND METHODS In this cross-sectional study, the study sample consisted of 228 individuals, including 118 addi...

Few studies have examined the subjective value attributed to drug rewards specifically as it compares with the value attributed to primary non-drug rewards in addicted individuals. The objective of this study is to assess 'liking' and 'wanting' of expected 'drug' rewards as compared to 'food' and 'sex' while respondents report about three different situations ('current', and hypothetical 'in ge...

in order to evaluate the economic performance of rehabilitation centers for addicted persons, the welfare organization asked all its centers to send the expense table of esfand 79-80 and fill out the information wanted there. the economic analysis is based upon this information. also, each center is provided with a questionnaire to estimate monthly expenses. according to the preventive scale of...

This study examined smartphone user behaviors and their relation to self-reported smartphone addiction. Thirty-four users who did not own smartphones were given instrumented iPhones that logged all phone use over the course of the year-long study. At the conclusion of the study, users were asked to rate their level of addiction to the device. Sixty-two percent agreed or strongly agreed that the...