BACKGROUND Both haemophagocytic lymphohistiocytosis and acute necrotizing encephalopathy are life-threatening condition. It presents major diagnostic difficulties, since it may have a diversity in clinical picture and with many conditions leading to the same clinical presentation. So it is key important to understand the disorders. CASE PRESENTATION We report a pediatric case of haemophagocyt...

OBJECTIVE The purpose of our study was to describe acute necrotizing encephalopathy in Korean infants and children, and we sought to evaluate the prognostic factors. MATERIALS AND METHODS Acute necrotizing encephalopathy was diagnosed in 14 Korean infants and children. We retrospectively analyzed the neuroimaging findings including the follow-up changes. The clinical course of the disease was...

Acute necrotizing encephalopathy of childhood has been described as a rare entity that usually affects immunocompetent infants and children, mainly in East Asia, typically after viral infection. We describe the case an 8-month-old, previously healthy Lebanese boy, who presented with fever seizures was found to have acute Adenovirus detected CSF. The clinical presentation laboratory radiological...

AIM To study the protective effects of tumor necrosis factor alpha (TNFalpha) antibody on pancreatic encephalopathy in rats. METHODS One hundred and twenty SD rats were randomly divided into normal control group, acute necrotizing pancreatitis group and TNFalpha antibody treated group. Acute hemorrhage necrotizing pancreatitis model in rats was induced by retrograde injection of 50 g/L sodium...