Brucellosis is one of the severe public health problems; the cumulative number of new human brucellosis cases reached 211515 from 2010 to 2014 in China. Bayingolin Mongol Autonomous Prefecture is situated in the southeast of Xinjiang, where brucellosis infection occurs every year. Based on the reported data of newly acute human brucellosis cases for each season in Bayingolin Mongol Autonomous P...

BACKGROUND Brucellosis is one of the most widespread zoonoses worldwide. It can affect any organ system, particularly the gastrointestinal system, but there is no report of acute liver failure as a brucellosis complication. CASE PRESENTATION We present a case of acute liver failure secondary to brucellosis infection. A 75-year-old Hispanic man presented to a University Hospital in Chía, Colom...

BACKGROUND Brucellosis is one of the important multi-organ zoonotic infectious diseases. The forms of the clinical course of brucellosis in humans are acute, sub-acute and chronic. OBJECTIVES The present study aimed to retrospectively analyze the clinical characteristics and complications in the clinical forms of human brucellosis in Iran. PATIENTS AND METHODS The population included 957 pa...

Brucellosis is a multisystemic infectious disease with high morbidity rates. Despite improvement in laboratory techniques diagnosis and monitoring response to treatment may be difficult in brucellosis in endemic regions. Mean Platelet Volume (MPV) is an index of platelet activation and mentioned to be influenced by inflammation. This study was undertaken to compare MPV with acute phase reactant...

The number of clinical studies on gamma interferon (IFN-gamma), tumor necrosis factor-alpha (TNF-alpha) and interleukin-4 (IL-4) in human brucellosis is limited. The present study was focused on IFN-gamma, TNF-alpha and IL-4 levels in acute brucellosis cases, in the acute phase and at the end of the treatment. The relation of these cytokines to traditional inflammation markers was also investig...

discussion neurobrucellosis is a rare presentation of brucellosis and should be considered when neurological problems cannot be explained by other etiology especially in endemic areas. introduction brucellosis is a zoonotic infection with high distribution all over the world and has many clinical manifestations, one of which is neurobrucellosis (nb). case presentation our case was a 78-year-old...

The index case in this report was clinically, epidemiologically, and serologically proved to be suffering from acute brucellosis acquired in Britain and complicated by acute intractable reactive arthritis. HLA tissue typing was A1, A2, B7, and B27. As there is no information available about HLA typing in brucellosis in Britain, we examined further cases of human brucellosis retrospectively. Thr...

Cardiac involvement in the course of acute brucellosis is rare and, when present, is usually manifested by endocarditis. Myocarditis is very infrequent and in the few reported cases, the course of the disease was fulminant. A patient with recurrent brucellosis who presented transient electrocardiographic T wave changes during two episodes of acute illness is reported. It is suggested that the p...

brucellosis is a rare cause of acute acalculous cholecystitis.  we report a 45-year-old, previously healthy, man with brucellosis who presented with abdominal pain due to cholecystitis.

Background: Because of high morbidity of the brucellosis in humans and the potential use of the microorganism as an agent of biologic warfare, protection of effective vaccines and specific diagnostic reagents become necessary to eradicate brucellosis. Objective: In this study we aimed to investigate the cytokine responses and changes in peripheral blood lymphocyte subgroups of acute brucellosis...