Topiramate is an oral sulphamate medication primarily used for seizure, migraine and neuropathic pain. It has been associated with secondary angle closure, which can mimic acute angle closure glaucoma. Suspicion for medication induced angle closure glaucoma should be higher whenever angle closure presents bilaterally. We present two cases of bilateral angle closure glaucoma secondary to topiram...

The aim of the study was to determine the incidence of acute angle-closure attacks among residents of the Split-Dalmatia County, Croatia, during a 6-year period. In this retrospective, interventional case series study, hospital records of 53 consecutive patients (33 female, mean age 71.7 +/- 16.6 and 20 male, mean age 66.2 +/- 23.2) with acute angle-closure attacks, treated at University Depart...

PURPOSE OF REVIEW Recent advances in the management of acute primary angle closure include argon laser peripheral iridoplasty, immediate anterior chamber paracentesis, and cataract or lens extraction by phacoemulsification. This review summarizes current thoughts on the role of these treatment modalities. RECENT FINDINGS Argon laser peripheral iridoplasty has been shown to be superior to trea...

Trabeculectomy surgery has been shown to lower intraocular pressure and is the most commonly performed glaucoma procedure worldwide. However, giving a patient a 'bleb for life' is not without consequences and the failure of trabeculectomy to control IOP in the long term is well documented. In some instances, such as in patients with exfoliative glaucoma or primary angle closure glaucoma, catara...

purpose : to describe a case of acute angle-closure glaucoma associated with oral topiramate (topamax, aria daroo) therapy case report: two weeks after initiation of oral topiramate therapy for epilepsy, a 35-year-old woman presented with blurred vision and headache. intraocular pressure in both eyes was significantly elevated and her visual acuity was 20/30 ocular uterque (ou). bilateral conju...

glutathione s-transferases (gsts) are members of multigenic family which have the essential functionin cells as an antioxidant. in the present study we studied the polymorphism of gstt1 and gstm1 deletion genotypes in iranian patients with primary closed angle glaucoma (pcag) compared to healthy subjects. we conducted a study of 41 pcag patients (24 women, 17 men) and 100 healthy participants (...