Acinic cell carcinoma with high-grade transformation of the salivary gland is an unusual variant with less than fifty cases being reported in the literature. It is characterized by a low- and high-grade component juxtaposed with one another and tends to take on a more aggressive clinical course than its low-grade counterpart, suggesting a poor clinical outcome. We, hereby, report a case of acin...

Acinic cell carcinoma arising in nasal cavity is a rare entity, and the number of reported cases is very limited in the English-language literature. The diagnosis is based entirely on histological evaluations. We report a primary acinic cell carcinoma in a 63-year-old female who had right nasal obstruction with hyposmia for the past 2 years. The tumor was found to be arising from the right post...

Acinic cell carcinoma of the breast is an extremely rare, malignant neoplasm characterized by widespread acinar cell-like differentiation and clinically low-grade malignancy. Herein, we report a case of acinic cell carcinoma of the breast in a 41-year-old woman. The tumor was poorly demarcated but had a firm consistency. It was removed with lumpectomy, and sentinel lymph node biopsy was perform...

BACKGROUND The differential diagnosis of salivary carcinomas is always difficult and challenging. Salivary neoplasms often shows more than one growth pattern and significant morphologic variability may exist within a single tumor and between different tumors. The aim of this study was to examine the role of DOG1 (discovered on gastrointestinal tumor-1) and p63 immunohistochemistry in the diagno...

Acinic cell carcinoma is a rare salivary gland tumor. The variant with lymphoid stroma is even rarer and has distinct histological features. We describe the case of a forty three year-old woman who presented with a left retroauricular mass of 5 years duration; magnetic resonance imaging revealed a well-circumscribed mass of 1.5 cm suggestive of pleomorphic adenoma. The patient underwent inferio...

Acinic cell carcinoma is an infrequent malignancy of salivary gland tissue in adults that is very rare in children. Review of the English literature reveals only 25 reported cases of this neoplasm in pediatric populations. This is a case report of the youngest known child to undergo parotidectomy and facial nerve dissection for an acinic cell carcinoma. The unusual clinical and surgical finding...

Clear cell carcinoma rarely appears in the jaws. We here reported two possible cases of such rare carcinoma. Microscopic examination and the clinical features indicated case NO. I being a renal cell carcinoma metastasized to the mandible, and case NO.2 being a primary acinic cell carcinoma originated from the minor salivary gland.

Acinic cell carcinoma of minor salivary gland of the base of tongue is very rare. Squamous cell carcinoma is the most common tumor in the base of tongue. We present a patient with gigantic acinic cell carcinoma of the base of tongue. This patient required emergency tracheotomy before surgery, because he had dyspnea when he came to our hospital. We removed this tumor by pull-through method and p...