By discovering how chemical compounds/xenobiotics cytotoxicity is affected when their metabolic pathways are inhibited or activated, the metabolic pathways that activate versus detoxify chemical compound can be identified. Reactive metabolites contributing to cytotoxicity can also be identified. In this lecture, the pretreatment of inhibitors and activators of xenobiotic metabolizing enzymes as...

by discovering how chemical compounds/xenobiotics cytotoxicity is affected when their metabolic pathways are inhibited or activated, the metabolic pathways that activate versus detoxify chemical compound can be identified. reactive metabolites contributing to cytotoxicity can also be identified. in this lecture, the pretreatment of inhibitors and activators of xenobiotic metabolizing enzymes as...

objectives : the aim of this study was to assess the effect of artificial accelerated aging (aaa) on color change of direct and indirect fiber-reinforced composite (frc) restorations. materials and methods: direct (z250) and indirect (gradia) composite resins were reinforced with glass (gf) and polyethylene fibers (pf) based on the manufacturers’ instructions. forty samples were fabricated and ...

hutchinson-gilford progeria syndrome (hgps) is a rare premature ageing disorder that is characterized by accelerated degenerative changes of the cutaneous, musculoskeletal and cardiovascular systems. mean age at diagnosis is 2.9 years and generally leading to death at approximately 13 years of age due to myocardial infarction or stroke. orthopedic manifestations of hgps are multiple and shoulde...

In this experiment, wheat plants were exposed to drought stress during seed development then we worked on the obtained seeds. The seed mitochondrial ultra-structure, and antioxidant enzymes in seedling were investigated after exposure to seed accelerated ageing. Drought stress during seed development induced some changes in mitochondrial ultra-structure. Encountering seed development to drought...

silicon dioxide or silica is the earth’s most abundant mineral. the primary pulmonary illness attributable to silica exposure is silicosis, which is observed in three forms: classic, accelerated and acute. a case of silicosis is presented in this article who has been working in a stone-cutting plant. he had suffered from symptoms of silicosis one year after employment in this plant (acute form)...

In this experiment, wheat plants were exposed to drought stress during seed development then we worked on the obtained seeds. The seed mitochondrial ultra-structure, and antioxidant enzymes in seedling were investigated after exposure to seed accelerated ageing. Drought stress during seed development induced some changes in mitochondrial ultra-structure. Encountering seed development to drought...

in this paper, we have considered the problem of rotating, magnetohydrodynamic heat and mass transfer by free convective flow past an exponentially accelerated isothermal vertical plate in the presence of variable mass diffusion. while the temperature of the plate is constant, the concentration at the plate is considered to be a linear function with respect to time t. the plate is assumed to be...

background and purpose: the goal of this study is application of the proportional hazards model (ph) and accelerated failure time model (aft), with consideration weibull distribution, to determine the level of effectiveness of the factors affecting on the level of disease-free survival (dfs) of the patients with breast cancer. materials and methods: based on the retrospective descriptive studie...