نتایج جستجو برای: accelerate aging

تعداد نتایج: 131661  

Journal: :Genetics 2005
João Pedro de Magalhães José A S Cabral Domingos Magalhães

Genetic interventions that accelerate or retard aging in mice are crucial in advancing our knowledge over mammalian aging. Yet determining if a given intervention affects the aging process is not straightforward since, for instance, many disease-causing mutations may decrease life span without affecting aging. In this work, we employed the Gompertz model to determine whether several published i...

2010
Judy Campisi David A. Sinclair Andrzej Bartke Maria A. Blasco William M. Bonner Vilhelm A. Bohr Mikhail V. Blagosklonny Robert M. Brosh Ronald A. DePinho Lawrence A. Donehower Caleb E. Finch Toren Finkel Myriam Gorospe Andrei V. Gudkov Michael N. Hall Stephen L. Helfand Jan Karlseder Cynthia Kenyon Valter Longo Andre Nussenzweig Heinz D. Osiewacz Daniel S. Peeper Thomas A. Rando Paolo Sassone-Corsi Manuel Serrano Norman E. Sharpless Vladimir P. Skulachev Eric Verdin Jan Vijg Elizabeth Blackburn Carol Greider

The editorial board of Aging reviews research papers published in 2009, which they believe have or will have a significant impact on aging research. Among many others, the topics include genes that accelerate aging or in contrast promote longevity in model organisms, DNA damage responses and telomeres, molecular mechanisms of life span extension by calorie restriction and pharmacologic interven...

2010
Judy Campisi David A. Sinclair Andrzej Bartke Maria A. Blasco William M. Bonner Vilhelm A. Bohr Mikhail V. Blagosklonny Robert M. Brosh Ronald A. DePinho Lawrence A. Donehower Caleb E. Finch Toren Finkel Myriam Gorospe Andrei V. Gudkov Michael N. Hall Stephen L. Helfand Jan Karlseder Cynthia Kenyon Valter Longo Andre Nussenzweig Heinz D. Osiewacz Daniel S. Peeper Thomas A. Rando Paolo Sassone-Corsi Manuel Serrano Norman E. Sharpless Vladimir P. Skulachev Eric Verdin Jan Vijg Elizabeth Blackburn Carol Greider

The editorial board of Aging reviews research papers published in 2009, which they believe have or will have a significant impact on aging research. Among many others, the topics include genes that accelerate aging or in contrast promote longevity in model organisms, DNA damage responses and telomeres, molecular mechanisms of life span extension by calorie restriction and pharmacologic interven...

2015
Jiang Zhu Jie Zhang Hong Li Tian-Yang Wang Chuan-Xin Zhang Ming-Jiu Luo Jing-He Tan

Although previous studies have suggested that cumulus cells (CCs) accelerate oocyte aging by secreting soluble and heat-sensitive paracrine factors, the factors involved are not well characterized. Because Fas-mediated apoptosis represents a major pathway in induction of apoptosis in various cells, we proposed that CCs facilitate oocyte aging by releasing soluble Fas ligand (sFasL). In this stu...

Journal: :Hospitals 1980
D H Hitt M P Harristhal

An aging population, national health insurance, and the factors that drove up the cost of health care in the 1970s will accelerate cost increases in the 1980s.

2010
Mikhail V. Blagosklonny Judy Campisi David A. Sinclair Andrzej Bartke Maria A. Blasco William M. Bonner Vilhelm A. Bohr Robert M. Brosh Jr Anne Brunet Ronald A. DePinho Lawrence A. Donehower Caleb E. Finch Toren Finkel Myriam Gorospe Andrei V. Gudkov Michael N. Hall Siegfried Hekimi Stephen L. Helfand Jan Karlseder Cynthia Kenyon Guido Kroemer Valter Longo Andre Nussenzweig Heinz D. Osiewacz Daniel S. Peeper Thomas A. Rando K Lenhard Rudolph Paolo Sassone-Corsi Manuel Serrano Norman E. Sharpless Vladimir P. Skulachev Jonathan L. Tilly John Tower Eric Verdin Jan Vijg

The Editorial Board of Aging reviews research papers published in 2009, which they believe have or will have significant impact on aging research. Among many others, the topics include genes that accelerate aging or in contrast promote longevity in model organisms, DNA damage responses and telomeres, molecular mechanisms of life span extension by calorie restriction and pharmacological interven...

Abolhassan Ahmadiani, Fatemeh Moradi, Mehrdad Rogani, Mohammad Reza Vaez Mahdavi, Shahnaz Mojarab, Taki Altiraihi,

Based on both animal and human studies, inequality in food intake and social instability has adverse effects on the health of individuals and the community. However, it is not known whether social instability, food deprivation and food inequality affect neuronal death and premature aging in young animals. To address this question, the effects of these adverse situations, histopathological chang...

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