Waleed Mazi, Vartul Sangal, Amir Saeed, Gunnar Sandstrom, François-Xavier Weill, Jun Yu Karolinska Institute, Department of Laboratory Medicine, Division of Clinical Microbiology, Karolinska University Hospital, Huddinge, Stockholm, Sweden; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Strathclyde, United Kingdom; Faculty of Health and Life Sciences, Nort...

Since the recognition of asymptomatic bacteriuria (ABU), several studies have questioned its significance. It is a very common condition, observed in many healthy individuals. Current guidelines mandate that ABU should not be treated in all cases, as it does not seem to improve the outcome. Conditional restrictions for treatment of ABU can be relaxed in certain situations, with minimal exceptio...

OBJECTIVE To determine the risk factors related to asymptomatic bacteriuria (ABU) in pregnant women. MATERIAL AND METHOD Three hundred and sixty asymptomatic pregnant women who attended their first antenatal appointment at Rajavithi Hospital from August 1 and October 31 2005 were enrolled. Those with symptoms of urinary tract infection within one month, those who had been prescribed antibioti...

f the mid-1990s through 2001 two of the West’s most implacable terrorist foes, Abu Hafs al-Masri and Abu Khabab, carried on what appears to have been a long-running feud within al-Qaeda, a feud that came to an end only when Abu Hafs al-Masri was killed by the U.S. military. Abu Hafs joined al-Qaeda early on and served as the group’s military commander from 1996 onward. Abu Khabab was a member o...

The unfolded protein response (UPR) counteracts stress caused by unprocessed ER client proteins. A genome-wide survey showed impaired induction of many UPR target genes in xbp-1 mutant Caenorhabditis elegans that are unable to signal in the highly conserved IRE1-dependent UPR pathway. However a family of genes, abu (activated in blocked UPR), was induced to higher levels in ER-stressed xbp-1 mu...

1 Center for Systems Biology and Faculty of Industrial Engineering, Mechanical Engineering and Computer Science, School of Engineering and Natural Sciences, University of Iceland, Reykjavík, Iceland, 2 Faculty of Pharmaceutical Sciences, University of Iceland, Reykjavik, Iceland, 3 Division of Science and Math, Center for Genomics and Systems Biology, New York University Abu Dhabi Institute, Ne...

Asymptomatic bacteriuria (ABU) is a bacterial carrier state in the urinary tract that resembles commensalism at other mucosal sites. ABU strains often lack the virulence factors that characterize uropathogenic Escherichia coli (E. coli) strains and therefore elicit weak innate immune responses in the urinary tract. In addition, ABU strains are active modifiers of the host environment, which the...

BACKGROUND The purposes of this study were to investigate the clinical outcomes of enterococcal bacteriuria and to determine whether current management is adherent to Infectious Diseases Society of America guidelines. METHODS We conducted a retrospective medical record review of patients from 2 academic teaching hospitals for 3 months (September 1 through November 30, 2009). Patients were cla...

Immunosuppressant peptide immunocortin for the first time was described in 1993. It corresponds to residues 11-20 of human Ig heavy chain (conserved motif of VH domain). There are no data about production of immunocortin by proteolysis of Ig in vivo. Synthetic immunocortin in concentration ~ 10-9 M suppresses phagocytosis in peritoneal macrophages, ConA-dependent blast transformation of rat lym...