نتایج جستجو برای: abo al
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Donor shortage remains the single most important factor limiting the success of transplantation medicine. In face of this unrelenting pressure, otherwise prohibitive immunological barriers are increasingly accepted, such as ABO incompatibility of a kidney from an available living donor. Treatment protocols for such situations involve varying combinations of B-cell depletion, removal of isohemag...
AIM To evaluate the differences in outcomes between ABO-incompatible (ABO-I) liver transplantation (LT) and ABO-compatible (ABO-C) LT. METHODS A systematic review and meta-analysis were performed by searching eligible articles published before No-vember 28, 2016 on MEDLINE (PubMed), EMBASE, and Cochrane databases. The primary endpoints were graft survival, patient survival, and ABO-I-related ...
Introduction: This study is the fi rst study about the distribution ABO blood types at children with acute leukemia in Federation of Bosnia and Herzegovina. The aim of the study is to point out distribution of blood type groups at children with acute leukemia (AL) Methods: The number of children in this study was the following: 145 children with acute leukemia and 27 of children with acute myel...
The current study evaluated amyloid-b oligomers (Abo) in cerebrospinal fluid as a clinical biomarker for Alzheimer’s disease (AD). We developed a highly sensitive Abo ELISA using the same N-terminal monoclonal antibody (82E1) for capture and detection. CSF samples from patients with AD, mild cognitive impairment (MCI), and healthy controls were examined. The assay was specific for oligomerized ...
ABO incompatibility is commonly observed in stem cell transplantation and its impact in this setting has been extensively investigated. HLA-mismatched unrelated donors (MMURD) are often used as an alternative stem cell source but are associated with increased transplant related complications. Whether ABO incompatibility affects outcome in MMURD transplantation for acute myeloid leukemia (AML) p...
The ABO blood group is the most important blood group system in transfusion medicine and organ transplantation. To date, more than 160 ABO alleles have been identified by molecular investigation. Almost all ABO genotyping studies have been performed in blood donors and families and for investigation of ABO subgroups detected serologically. The aim of the present study was to perform ABO genotyp...
BACKGROUND: The ABO blood groups result from DNA sequence variations, predominantly single nucleotide and insertion/deletion polymorphisms (SNPs and indels), in the ABO gene encoding a glycosyltransferase. The ABO blood groups A(1), A(2), B and O predominantly result from the wild type allele A1 and the major gene variants that are characterized by four diallelic markers (261G>del, 802G>A, 803G...
Karl Landsteiner was born in Vienna in 1868. He graduated from the Vienna Medical School in 1891, which dominated one of his most productive and formative periods in the following years. Although he devoted himself to research in bacteriology, haematology and immunology, he tried to maintain a close relationship with clinical medicine. Landsteiner’s intellectual curiosity was centred on fundame...
Many studies of ABO isolysins have indicated that some A, B, and O sera show no isohemolytic activity. The apparent incidence of ABO isolysins in human sera varies widely, from 0.24 of A sera containing anti-B isolysin [8] to more than 90 "6 of 0 and B sera containing anti-A isolysin [4]. Reports of many other wide-ranging values have led t o the general assumption that isolysins, in contrast t...
BACKGROUND Traditional ABO blood group serology is based on the immunoreactivity of antisera with the carbohydrate A, B and H antigens. Progress in the molecular biology of the ABO system has recognized the molecular basis of the red cell (RBC) antigens and has provided a genetic model for ABO polymorphism at the molecular level. Recently, this genetic model was tested in a large number of indi...
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