A thermostable urinary homologue of the plasma aldosterone-binding globulin (ABG), designated ABG-TsU, was isolated and purified by differential ultrafiltration, ion exchange chromatography, and gel filtration to electrophoretic homogeneity. Scatchard plot analysis using highly purified ABG-TsU demonstrated reversible high-affinity low-capacity binding at separate sites for aldosterone and dehy...

Tetradecyl 2,3-dihydroxybenzoate (ABG-001) has been designed and synthesised as a lead compound to treat Alzheimer's disease, based on structure-activity relationships of gentisides. In this paper, the alkyl chain and ester linkage group of ABG-001 were modified. Consequently, several series of novel gentiside derivatives were designed and synthesised, and their neuritogenic activity was evalua...

OBJECTIVE In atrophic body gastritis (ABG) chronic hypergastrinaemia stimulates enterochromaffin-like (ECL) cell proliferation with development of cell hyperplasia, dysplasia and possibly type-1 gastric carcinoids. As circulating chromogranin A (CgA) levels are a marker of neuroendocrine tumours, we evaluated the clinical usefulness of CgA assay in ABG patients to detect those with carcinoids. ...

OBJECTIVE To identify prognostic factors affecting outcome in lateral tympanoplasty for total or near-total tympanic membrane perforation. STUDY DESIGN Retrospective case series. METHODS Patients were those presenting with total or near-total tympanic membrane perforation undergoing lateral tympanoplasty from 1999 to 2004. We systematically collected demographic, clinical, audiologic, and o...

OBJECTIVES/HYPOTHESIS Patients with enlarged vestibular aqueduct (EVA) often demonstrate an air-bone gap (ABG) at low frequencies on audiometric testing. The mechanism for this has not been well elucidated. We investigated vestibular aqueduct (VA) size and ABG in patients with EVA, and assessed the relationship between VA diameter and ABG. STUDY DESIGN Retrospective review. METHODS We asses...

BACKGROUND No studies have examined the clinical utility of arterial blood gas (ABG) values during spontaneous breathing trials (SBTs) for making extubation decisions. Nonetheless many intensive care units measure ABGs during an SBT to determine, in conjunction with other data, whether the SBT was successful. OBJECTIVE Determine how often ABG values change extubation decisions. METHODS Each...

Arterial blood gases (ABG) are obtained commonly in dyspneic persons presenting to emergency departments. The study by Burri and colleagues found that the information contained in ABG fails to distinguish between pulmonary and other causes of dyspnea. On the other hand, arterial pH was highly predictive of ICU admission and outcome. Until large clinical studies show equivalence between peripher...

We describe the patterns of utilization of arterial blood gas (ABG) tests in a large tertiary care hospital. To our knowledge, no hospital-wide analysis of ABG test utilization has been published. We analyzed 491 ABG tests performed during 24 two-hour intervals, representative of different staff shifts throughout the 7-day week. The clinician ordering each ABG test was asked to fill out a utili...

INTRODUCTION Arterial blood gas and serum lactate (ABG / SL) values have been shown to be markers for occult shock and poor outcome following blunt trauma. However, the utility of ABG / SL in blunt trauma patients who also receive computed tomographies (CT) of the chest, abdomen, and pelvis (CT C&A) remains unknown. METHODS A chart review was performed of all adult blunt trauma patients who r...

Arterial blood gas (ABG) interpretation can be a difficult and daunting concept for students and new critical care nurses to grasp. Although ABG interpretation can be arduous, it is essential that critical care nurses master this skill, because accurate interpretation can be life determining. Fortunately, with the numerous technological advances that are available, ABG interpretation can be les...