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تعداد نتایج: 66 فیلتر نتایج به سال:
The combination of modern interventional and preventive medicine has led to an epidemic of ageing. While this phenomenon is a positive consequence of an improved lifestyle and achievements in a society, the longer life expectancy is often accompanied by decline in quality of life due to musculoskeletal pain and disability. The Aarhus Regenerative Orthopaedics Symposium (AROS) 2015 was motivated...
Sirtuins are NAD+-dependent protein deacetylases regulating metabolism, stress responses and ageing processes. Among the seven mammalian Sirtuins, Sirt1 is the physiologically best-studied isoform. It regulates nuclear functions such as chromatin remodelling and gene transcription, and it appears to mediate beneficial effects of a low calorie diet which can partly be mimicked by the Sirt1 activ...
The Canadian Consensus Development Conference on Surveillance and Screening for Antimicrobial-Resistant Organisms (AROs) was sponsored by the Alberta Ministry of Health to provide evidence to update policies for ARO screening in acute care settings. A rigorous evidence-based literature review completed before the conference concluded that that neither universal nor targeted screening of patient...
The heat shock response, the cellular response to protein damaging stress, is critical in maintaining proteostasis. The heat shock response is regulated by the transcription factor HSF1, which is activated upon heat shock and other stresses to induce the expression of molecular chaperones. SIRT1 has previously been shown to activate HSF1 by deacetylating it, leading to increased DNA binding abi...
comparison and grouping of 32 grape cultivars and genotypes by using 61 traits including; 5 phenological and vegetative characters, 41 traits related to fruit and amount of resveratrol in 15 parts of plant was done according to grape descriptor and related methods. according to the results some traits such as spikelet weight, berry color, length of peduncle, length of berry tail, weight and len...
The process of knowledge discovery from databases is a knowledge intensive, highly user-oriented practice, thus has recently heralded the development of ontology-incorporated data mining techniques. In our previous work, we have considered the problem of mining association rules with ontological information (called ontological association rules) and devised two efficient algorithms, called AROC...
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