OBJECTIVE The objectives of this study were to: modify the preparation of 99mTc-tetrofosmin by using twice the amount of 99mTcO4- recommended by the manufacturer; evaluate the use of miniaturized rapid paper chromatography (MRPC) for quality control (QC) testing; and determine the in vitro stability of the modified preparation using MRPC. METHODS Two preparations of 99mTc-tetrofosmin were mad...

objective: iqspect is an advanced high-speed spect modality for performing myocardial perfusion imaging (mpi), which uses a multi-focus fan beam collimator with resolution recovery reconstruction. the aim of this study was to compare iqspect compared with conventional spect interms of performance based on standard clinical protocols. in addition, we examined the concordance between conventional...

Giant cell tumor (GCT) is usually considered to be a benign entity. In rare cases, pulmonary metastases can be observed. This report documents the 99mTc-tetrofosmin scan findings of a conventional GCT of the femur and developed pulmonary nodules. The lung lesions were felt to be an example of benign metastases. According to our review, this is the first case in the literature demonstrating tetr...

Soft-tissue attenuation artifacts generally appear as fixed perfusion-scan defects. Gated 99mTc-tetrofosmin SPECT may help differentiate myocardial infarction (MI) from artifacts, as fixed defects with decreased function (wall motion and thickening) probably represent MI, whereas attenuation artifacts represent preserved function. Methods: Ungated stress and gated rest 99mTc-tetrofosmin SPECT w...

OBJECTIVE The purpose of this work was to develop functional parameters to analyze regional cardiac function using ECG-gated 99mTc-tetrofosmin SPECT. Our goal was to develop a methodology that used slice thickness correction, the generation of a time-activity curve and a polar map. METHODS Fourteen normal patients without evidence of coronary artery disease were studied. One hour after intrav...

Quantitative measurement of myocardium perfusion is possible with single photon emission computed tomography (SPECT) using a semiconductor detector. However, accumulation of 99mTc-tetrofosmin in the liver may make it difficult to assess that accurately in the inferior myocardium. Our idea is to reduce the high accumulation in the liver by using dynamic SPECT imaging and a technique called time ...

OBJECTIVE Left ventricular mass is an important determinant of diagnosis and prognosis in patients with heart disease. The aim of the present study was to validate measurement of the left ventricular mass index (LVMI) by quantitative gated myocardial SPECT (QGS) with 99mTc-tetrofosmin by comparing it with echocardiography. METHODS QGS and M-mode echocardiography (Echo) were performed within o...