Left ventricular (LV) function and volumes, along with myocardial perfusion, have major diagnostic and prognostic importance inpatients with coronary artery disease [4,11,13,14, 18,20,27]. Myocardial perfusion scintigraphy is a well-established technique for evaluation of myocardial perfusion [16,26,37,38]. Electro cardiographic gating during the acquisition of SPECT perfusion images has become...

Previously, technetium-99m-stannous pyrophosphate (99mTc-PPi) has been used to localize and estimate the size of myocardial infarcts in animals after permanent coronary artery occlusion. This study tested the hypothesis that 99mTc-PPi accurately sizes myocardial infarctions produced by temporary coronary artery occlusion and reflow in dogs. Three groups of dogs were studied: group A underwent 3...

objective: iqspect is an advanced high-speed spect modality for performing myocardial perfusion imaging (mpi), which uses a multi-focus fan beam collimator with resolution recovery reconstruction. the aim of this study was to compare iqspect compared with conventional spect interms of performance based on standard clinical protocols. in addition, we examined the concordance between conventional...

BACKGROUND AND PURPOSE The brain distribution of 9mTc-hexamethylpropyleneamine oxime (HMPAO) correlates with regional brain perfusion, whereas 99mTc-ethyl cysteinate dimer (ECD) reflects not only perfusion but also the metabolic status of brain tissue. We compared 99mTc-ECD single-photon emission CT (SPECT) with 99mTc-HMPAO SPECT early after recanalization by local intraarterial thrombolysis (L...

OBJECTIVE To compare single-photon-emission computed tomography (SPECT) imaging scans using 201Tl and 99mTc-MIBI in detection of viable myocardium, in regions compromised by infarction. METHODS Thirty-two (59.3 +/- 9.8 years old and 87% male) myocardial infarction patients were studied. All had Q waves on the ECG and left ventricle ejection fraction of < 50%. They underwent coronary and left ...

fixed myocardial defects in both stress and rest images, could be artifactual as a result of soft tissue attenuation. to increase specificity and identify the false positive results, we used gated technique to evaluate the wall motion and wall thickening as an index to differentiate real ischemic lesions from artifactual defects. 93 patients were studied. in 46 patients (48.8%) fixed perfusion ...

BACKGROUND The "back-translation" of clinically available protocols to measure myocardial perfusion to preclinical imaging in mouse models of human disease is attractive for basic biomedical research. With respect to single-photon emission computed tomography (SPECT) approaches, clinical myocardial perfusion imaging protocols are established with different 99mTc-labeled perfusion tracers; howev...

UNLABELLED The aim of this study was to elucidate the clinical usefulness of scatter correction with an artificial neural network (ANN) in 99mTc and 123I dual-isotope SPECT. METHODS Two algorithms for ANN scatter correction were tested: ANN-10 and ANN-3 employing 10 and 3 energy windows for data acquisition, respectively. Three patients underwent myocardial or brain SPECT with one of the foll...

objective(s): a novel iq-specttm method has become widely used in clinical studies. the present study compares the quality of myocardial perfusion images (mpi) acquired using the iq-specttm (iq-mode),conventional (180° apart: c-mode) and l-mode (90° apart: l-mode) systems. we assessed spatial resolution, image reproducibility and quantifiability using various physical phantoms. materials and me...

  Objective: IQSPECT is an advanced high-speed SPECT modality for performing myocardial perfusion imaging (MPI), which uses a multi-focus fan beam collimator with resolution recovery reconstruction. The aim of this study was to compare IQSPECT compared with conventional SPECT interms of performance based on standard clinical protocols. In addition, we examined the concordance between convention...