In-vitro labeling of RBC with 99mTc is an intricate procedure and there is always a need foran alternate blood pool imaging agent. The aim of this study was to prepare an effective nanosized liposome (NLs) similar to human RBC for blood pool scintigraphy. This study formulatesPEG-NLs and non-PEG-NLs using film method plus high pressure homogenization technique.Biodistribution studies were perfo...

OBJECTIVES Most studies that clinically validated peri-ictal SPECT in intractable partial epilepsy had used technetium-99m-hexamethylpropylene amine oxime (99mTc-HMPAO or 99mTc-exametazime) as the radiopharmaceutical. Because of some theoretical advantages, technetium-99m-ethyl cysteinate diethylester (99mTc-ECD or 99mTc-bicisate) is increasingly being used instead. This study compares unstabil...

White blood cell (WBC) 99mTc-hexamethylpropyleneamineoxime (HMPAO) scintigraphy was performed in a patient with eosinophilic gastroenteritis. WBC accumulation was detected in the terminal ileum to descending colon, and pathological studies demonstrated eosinophilic infiltration at the same region. 99mTc-HMPAO-WBC scintigraphy was proved to be a useful tool for the detection of eosinophilic infi...

BACKGROUND 99mTc-HMPAO is a well-established isotope useful in the detection of regional cerebral blood flow. Diabetes gives rise to arterial atherosclerotic changes that can lead to significant end organ dysfunction, prominently affecting perfusion to the heart, kidneys, eyes and brain. In the current study, we investigated the role of 99mTc-HMPAO cerebral perfusion scans in detecting early va...

in-vitro labeling of rbc with 99mtc is an intricate procedure and there is always a need foran alternate blood pool imaging agent. the aim of this study was to prepare an effective nanosized liposome (nls) similar to human rbc for blood pool scintigraphy. this study formulatespeg-nls and non-peg-nls using film method plus high pressure homogenization technique.biodistribution studies were perfo...

background the ability to follow the distribution and migration of biologically active cells in human is essential for the development of cell-based therapies and diagnostics. nuclear medicine imaging is widely applied in clinic as an attractive technique for in vivo wbc and stem cell tracking. the aim of this study was to evaluate prosthesis infection of a 51 years old man with previous histor...

A balloon test occlusion of the internal carotid artery was performed in 11 patients with internal carotid artery aneurysms. Tolerance by patients was assessed by a combination of clinical examination; angiography; electroencephalography; 99mTc-hexamethylpropyleneamine oxime (99mTc-HMPAO) single-photon emission computed tomography (SPECT) with relative quantification; and, in four patients, 99m...

We have determined cerebral blood flow (CBF) and the single-pass cerebral extraction (E) of several putative agents for external imaging of CBF. Simultaneous measurements of blood flow and extraction were performed in 106 rats. For all agents, comparison of linear and exponential regressions of E on CBF indicates that this relationship can be described as linear over the range of flows studied....

In-vitro labeling of RBC with 99mTc is an intricate procedure and there is always a need foran alternate blood pool imaging agent. The aim of this study was to prepare an effective nanosized liposome (NLs) similar to human RBC for blood pool scintigraphy. This study formulatesPEG-NLs and non-PEG-NLs using film method plus high pressure homogenization technique.Biodistribution studies were perfo...

The distribution of selectively administered papaverine was determined in nine patients with delayed cerebral vasospasm in the territories of the anterior (ACA) and/or middle cerebral arteries (MCA) secondary to aneurysmal subarachnoid hemorrhage by simultaneous infusion with technetium-99m-hexamethyl-propyleneamine oxime (99mTc-HMPAO). Four of the nine patients had a ruptured anterior communic...