INTRODUCTION ............................................................................................... 914 I. A TYPOLOGY OF DYSFUNCTION .......................................................... 916 A. Constitutional Dysfunction .......................................................... 916 B. Political Dysfunction ................................................................... 919 C....

Weihua Sun1,2 and Zhendong Zhong1* 1Department of Internal Medicine, University of California at Davis Medical Center, Sacramento, California, USA 2Institute of Biomedicine, College of Life Science and Technology, Jinan University, Guangzhou, China *Corresponding author: Zhendong Zhong, Center for Musculoskeletal Health, Internal Medicine Department, University of California at Davis, 4625 2nd ...

Plasmodium falciparum and Plasmodium vivax are single-celled parasites that, between them, are responsible for the vast majority of malaria cases in humans. Of the two, P. falciparum often provokes the most acute symptoms, whereas P. vivax is associated with a recurring, chronic version of malarial disease. Both parasites spend a large portion of their life cycle living and replicating within h...

During nitric oxide signaling, type Ialpha cGMP-dependent protein kinase (PKGIalpha) activates myosin light chain (MLC) phosphatase through an interaction with the 130-kDa myosin targeting subunit (MYPT1), leading to dephosphorylation of 20-kDa MLC and vasodilatation. It has been suggested that the MYPT1-PKGIalpha interaction is mediated by the COOH-terminal leucine zipper (LZ) of MYPT1 and the...

www.sciencemag.org (this information is current as of October 17, 2007 ): The following resources related to this article are available online at http://www.sciencemag.org/cgi/content/full/296/5569/916 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/296/5569/916/DC1 can be foun...

1) Department Civil and Environmental Engineering, KAP 230A, University of Southern California, Los Angeles, CA 90089; Tel: 213-740-6140; Email: [email protected] 2) COSMOS, Building 454, Room 121, 1301 South 46 Street, Richmond, CA 94804-4698; Tel: 510-231-9436 and 830830-833-5446; Email: [email protected] 3) California Department of Conservation, California Geological Survey, 801 K. Street MS 12...