ONE of John Shergold’s abiding research interests, and an area in which he made fundamental contributions to the fields of palaeontology and geology, was the study of Cambrian arthropods in general, and trilobites in particular (e.g., Shergold 1977, 1988, 1991; Shergold et al. 1990; Shergold & Laurie 1997). Here we focus on what Cambrian arthropods, including trilobites, can tell us about the n...

Kårsnäs, A. 2014. Image Analysis Methods and Tools for Digital Histopathology Applications Relevant to Breast Cancer Diagnosis. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology 1128. 129 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-8889-5. In 2012, more than 1.6 million new cases of breast cancer were diagnosed and about half a ...

We previously described a diverse family of sulfated anionic N-linked oligosaccharides released by peptide: N-glycosidase F (PNGaseF) from calf pulmonary artery endothelial (CPAE) cells (Roux, L., Holoyda, S., Sundblad, G., Freeze, H.H., and Varki, A. (1988) J. Biol. Chem. 263, 8879-8889). Since a major fraction of the intact lung consists of endothelial cells, we reasoned that bovine lung migh...

TRILOBITES of the family Missisquoiidae Hupé 1955 occur throughout Laurentian North America in a relatively narrow interval of what is now the latest Cambrian succession (e.g., Shaw 1951; Winston & Nicholls 1967; Stitt 1971, 1977; Taylor & Halley 1974; Ludvigsen 1982; Fortey 1983; Westrop 1986; Dean 1989). Although widely distributed, both geographically and environmentally, missisquoiid trilob...

Recent examples of the major public health benefits of vaccination include global reductions in measles mortality and record low levels of vaccine-preventable diseases in the United States. Nevertheless, real or perceived vaccine safety issues may adversely impact vaccine programs. Robust postlicensure safety monitoring which combines active and passive surveillance with use of standardized cas...

Objectives—To introduce the UK SF36 Version II (SF36-II), and to (a) gain population norms for the UK SF36-II in a large community sample as well as to explore the instrument’s internal consistency reliability and construct validity, and (b) to derive the Physical Component Summary (PCS) and Mental Component Summary (MCS) algorithms for the UK SF36-II. Design—Postal survey using a questionnaire...

A framework for understanding the synthesis and catalysis of metabolites and other biochemicals by proteins is crucial for unraveling the physiology of cells. To create such a framework for Zea mays L. subsp. mays (maize), we developed MaizeCyc, a metabolic network of enzyme catalysts, proteins, carbohydrates, lipids, amino acids, secondary plant products, and other metabolites by annotating th...

Conversion of C2 to C3 compounds is used by nature in abundant processes such as photorespiration but comes at the cost CO2 release. Erb and co-workers recently published an article Nature Catalysis describing a synthetic pathway able convert through carbon fixation step. As climate crisis becomes more urgent, we must tackle major contributors change using collection creative solutions. The con...

Full: HTML / PDF (283K) Select Citation A New LC/MS/MS Rapid and Sensitive Method for the Determination of Green Tea Catechins and their Metabolites in Biological Samples Maria de Lourdes Mata-Bilbao, Cristina Andrés-Lacueva, Elena Roura, Olga Jáuregui, Celina Torre, and Rosa Maria Lamuela-Raventós pp 8857 8863; (Article) DOI: 10.1021/jf0713962 Abstract Full: HTML / PDF (138K) Select Citation A...

Abilities are as important as interests in career choice and development. Reviving cognitive assessment in career counseling promises to help counselees better understand their career options and how to enhance their competitiveness for the ones they prefer. Nearly a century of research on human cognitive abilities and jobs’ aptitude demands in the United States economy reveals that the two dom...