OBJECTIVES This study aimed to explore platelet function tests relevant to the biological effects of clopidogrel that could help the clinical monitoring of drug efficacy. BACKGROUND Clopidogrel selectively inhibits the P2Y12 receptor, the major role of which is stabilization of aggregation, whereas initiation of aggregation depends on activity of both P2Y1 and P2Y12 receptors. METHODS Tests...

abstract background: hypertension in pregnancy is one of the prevalent disorders resulting in maternal death. the aim of this study was to investigate the effect of stretching exercise and walking on changes of blood pressure in nulliparous women during pregnancy. materials and methods: this was a quasi-experimental trial that consisted three groups of women who took part in pre- and post-tests...

background: hypertension is one of the prevalent and dangerous complications of diabetes mellitus. as it is difficult to control hypertension, the necessity of using new techniques such as non-pharmaceutical methods and complementary therapy is doubled. this study aimed to determine the effect of aerobic exercise on the blood pressure of patients with type 2 diabetes. methods: this study was a ...

1. The conversion of inactive (phosphorylated) pyruvate dehydrogenase complex into active (dephosphorylated) complex by pyruvate dehydrogenase phosphate phosphatase is inhibited in heart mitochondria prepared from alloxan-diabetic or 48 h-starved rats, in mitochondria prepared from acetate-perfused rat hearts and in mitochondria prepared from normal rat hearts incubated with respiratory substra...

UNLABELLED Aims/Introduction:  Postprandial serum C-peptide levels are readily determined in clinical practice and have a good correlation with serum C-peptide levels after glucagon load; the measurement is often used as an index of endogenous insulin secretion. However, the factors affecting postprandial serum C-peptide levels remain to be evaluated. MATERIALS AND METHODS   To investigate th...