Background & Aims: In spite of frequent produce and use of magnetic nanoparticles in biological fields, there are few studies on their side effects, especially under in-vivo conditions. Method: In this research, the effect of the single-dose intraperitoneal injection of DMSA (dimercaptosuccinic acid) coated magnetic iron oxide nanoparticles (Fe3O4) in different doses (50, 100, 200 and 300 mg/kg...

This thesis deals with the synthesis, characterisation, and some applications of ferrimagnetic iron oxide nanoparticles. The iron oxide systems presented in this work are Fe3O4, γ-Fe2O3, NixFe3−xO4, CoxFe3−xO4. Iron oxide nanoparticles were prepared using chemical synthesis methods. Nanoparticles with a narrow size distribution were synthesised using zone confinement methods such as nanoemulsio...

Recently, there has been a great deal of interest in the use of the medicinal plants with high antioxidant compounds for curing liver injuries induced by hepatoxcitic agents. This study was to assess the protective effect of Carum carvi L. essential oil (E.O) on the hepatoxitic rats induced by overdose of iron oxide nanoparticles (NPs). The rats were distributed to 4 groups. In negative control...

Introduction: Depression is a mood disorder in which feelings of sadness, loss, anger, or frustration interfere with everyday life for one to several weeks. Several studies have shown that iron nanoparticles have neuroprotective and anti-inflammatory effects. This study aimed to evaluate anti-depressive effect of iron nanoparticles in male rats.  Methods: Depression was induced by Lipopol...

In the present work, nano scaled zero valent irons (nZVI) were synthesized in ethanol medium by the method of ferric iron reduction using sodium borohydride as a reducing agent under atmospheric conditions. The obtained iron nanoparticles are mainly in zero valent oxidation state and remain without significant oxidation for weeks. A systematic characterization of nZVI was performed using UV, XR...

Iron oxide (Fe2O3) nanoparticles were prepared by combination of sol-gel autocombustion and ultrasonic irradiation. The XRD pattern reveals that the crystallite size of sample is 36.7 nm and the phase identification shows hematite, syn has been crystalized. The morphology of the sample investigated by FESEM showed that particle size of the sample was about 76 nm. The optic...

Introduction: Inflammation plays a critical role in the progression of atherosclerosis. Novel iron-based nanoparticle platforms may allow noninvasive high-field MRI detection of vascular macrophages in mouse arteries. Purpose: To evaluate two novel nanoparticle platforms – magnetite incorporated human ferritin protein cages (HFn-Fe) and graphite/FeCo core-shell nanocrystals (G-FeCo) – for MRI o...

Objective(s):Iron oxide nanoparticles have found prevalent applications in various fields including drug delivery, cell separation and as contrast agents. Super paramagnetic iron oxide (SPIO) nanoparticles allow researchers and clinicians to enhance the tissue contrast of an area of interest by increasing the relaxation rate of water. In this study, we evaluate the dependency of hydrodynamic si...