نتایج جستجو برای: 5 fluorouracil colon cancer

تعداد نتایج: 2083830  

2013
Hanaa H. Ahmed Mona Abdel-Rahman Fatma El-Zahraa H. Salem Aziza B. Shalby Maha S. Lokman

The present study aims to evaluate the role of Curcuma longa (turmeric) methanolic extract against colon cancerinduced in rats. Forty male rats were classified into 5 groups as follows: Group (1) control. Groups from (2) to (5) intrarectally injected with N-methylnitrosourea in a dose of 2 mg dissolved in 0.5 ml water/rat three times weekly for five weeks for induction of colon cancer and group...

Journal: :Molecules 2017
Mohsin O Mohammed Kameran S Hussain Nadia Q Haj

5-fluorouracil (5-FU) is a specific anti-cancer agent that is generally used to treat gastrointestinal, colorectal, and breast cancer. In this work, chitosan (CS) was extracted from local fish scales using an established method. 5-FU was then converted to 1-acetic acid-5-fluorouracil (FUAC) and reacted with this CS to prepare chitosan-1-acetic acid-5-fluorouracil (CS-FUAC) conjugates as a colon...

Journal: :caspian journal of internal medicine 0
mohsen vakili-sadeghi mohammadhasan omranpour

background: solid tumors may occur in 3% of the patients with chronic myeloid leukemia (cml). in this paper, we presented a case of cml following treatment of colon cancer. case presentation: a 25 year old man was diagnosed of adenocarcinoma of rectosigmoid treated with fluorouracil-based chemotherapy. following relapse, he received florouracil, oxaliplatin and irinotecan during the next year. ...

2016
Vikas Dembla

Oxaliplatin or irinotecan with 5-fluorouracil form the chemotherapy backbone of any systemic treatment of colorectal cancer. We successfully treated an idiosyncratic reaction to oxaliplatin consisting of severe chills, vomiting, diarrhea, and fever in a patient with metastatic colon cancer.

2016
Koji Komori Takashi Kinoshita Oshiro Taihei Seiji Ito Tetsuya Abe Yoshiki Senda Kazunari Misawa Yuich Ito Norihisa Uemura Seiji Natsume Jiro Kawakami, Akira Ouchi Masayuki Tsutsuyama Takahiro Hosoi Itaru Shigeyoshi Tomoyuki Akazawa Daisuke Hayashi Hideharu Tanaka Yasuhiro Shimizu

We report a long-term survivor of colorectal cancer who underwent aggressive, frequent resection for peritoneal recurrences. A 58-year-old woman was diagnosed with descending colon cancer. Resection of the descending colon along with lymph node dissection was performed in September 2006. The pathological findings revealed Stage IIA colorectal cancer. The following peritoneal recurrences were re...

2015
Joshua Runtuwene Haruka Amitani Marie Amitani Akihiro Asakawa Kai-Chun Cheng Akio Inui

Oxidative stress is involved in cancer development. Hydrogen (H2) is a potent antioxidant and exhibits anti-inflammatory and potentially anticancer-like activities. This study aimed to investigate the role of H2 incombination with 5-fluorouracil (5-FU) in cancer treatment both in vitro and in vivo using the colon 26 cell line. The survival rate was determined using the Kaplan-Meier survival tes...

Journal: :Cancer research 1983
A F Sobrero J R Bertino

Prior to their use in patients with hepatic metastasis of colon cancer, we studied the cell-killing effects of 5-fluorouracil, 5-fluoro-2'-deoxyuridine, 3',5'-dichloromethotrexate (DCM), and 5-fluoro-2'-deoxyuridine, 3',5'-dichloromethotrexate (DCM), and combinations of these fluoropyrimidines with DCM on a human colon carcinoma cell line (HCT-8). Sequential exposure of these cells to DCM follo...

Journal: :Ankara Universitesi Veteriner Fakultesi Dergisi 2022

In N-methyl-N-nitrosourea (MNU)-induced colon cancer modeling in rats, it was aimed to evaluate the regressive effect of grayanotoxin-rich Turkish mad honey and 5-fluorouracil (5-FU), separately together. Study groups were control group (CG), (CCG), 5-Flourouracil (FUG), (HG), 5-FU combined (FU-HG). WBC, lymphocyte, eosinophil, basophil, serum LDH, TOS, total protein values determined rats CCG ...

2012
Hisanori Miki Kozo Tsunemi Masao Toyoda Hideto Senzaki Yutaka Yonemura Airo Tsubura

A 56-year-old Japanese woman who underwent a curative resection of ascending colon cancer at 43 years of age was found to have a tumor in her lower left abdominal cavity by computed tomography at 53 years of age. The tumor in the omentum was resected and identified as an adenocarcinoma compatible with metastasis from the primary ascending colon cancer. Although the patient received adjuvant che...

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