Rabbits fed a vitamin E-deficient diet developed severe muscular dystrophy in 3-4 wk, but they did not become anemic. Nevertheless, reticulocyte counts increased in deficient rabbits (3.2%) compared to control rabbits (0.9%), and erythroid hyperplasia was evident in the bone marrow. Comparing deficient rabbits to controls, the plasma iron concentration was lower (134.4 versus 206.6 microgram/dl...

The in vivo consumption of oxygen and glucose was studied in relation to growth in Walker Carcinoma 256, Hepatoma 5123, and Fibrosarcoma 4956 transplanted in rats. Glucose not elim inated as lactate or carbon dioxide in the efferent blood was pre sumed to be retained by the tumor. The retention was so high that growth alone could not account for it. As an alternative, the elimination of glucose...

Interactions between the heart and the kidneys are increasingly acknowledged among both cardiologists and nephrologists. The term cardiorenal syndrome now applies to the bidirectional nature of how disease in one organ system affects the function of the other organ system. Cardiovascular disease is a major threat to patients with chronic kidney disease, while renal dysfunction is prevalent in p...

to produce a continuous outflow from the sampling device. In some tumors, but not in all of them, the pressure needed to stop this outflow was twice as large as that re quired for the normal subcutaneous tissue, and it was similar to that measured in the skin after venous obstruction. The sampling technic has been described in detail. Each sample was compared with the blood serum flowing into a...

The majority of outpatients with heart failure (HF) have chronic kidney disease (CKD) as an important comorbidity. Both glomerular filtration rate and abnormal urinary albumin excretion are major predictors of outcome in HF patients. Despite this, patients with renal dysfunction have been systematically excluded from the large randomized HF trials. There is lack of evidence for optimal treatmen...

T he UK has one of the longest waiting lists for coronary artery bypass grafting (CABG). In 1999–2000, 24 798 CABG procedures were performed at a typical cost of £4956, leading to total direct costs in excess of £122 million. Early discharge programmes have been introduced as a strategy to reduce hospital costs, increase the throughput of patients and decrease waiting list times. Early studies ...

From the Faculty of Medicine, University of Oslo, Oslo, Norway and Departments of Obstetrics and Gynaecology, Oslo University Hospital, Oslo, Norway (A.C.S., K.M.); Nuffield Department of Obstetrics and Gynaecology (C.W.G.R), Radcliffe Department of Medicine (P.L.), University of Oxford, Oxford, United Kingdom; Department of Maternal Medicine, Institute for Women’s Health, University College Lo...

BACKGROUND Earlier studies have shown that interlukin-10 (IL-10) -1082 A>G gene polymorphism is implicated in susceptibility to pulmonary tuberculosis (PTB), but their results are inconsistent and inconclusive. In the present study, a meta-analysis was performed to analyze the potential association between IL-10 -1082 A>G gene polymorphism and PTB susceptibility. METHODS A quantitative synthe...

in order to evaluate the relationship between grain yield and agronomic characteristics in bread wheat genotypes in different planting dates under rainfed conditions, a factorial experiment was conducted based on rcbd with four replications at gonbad-e qabus region, iran, during 2012-2014 growing seasons. number of spikes per unit area, grain filling rate, effective grain filling period, number...