We determined in vitro susceptibilities for ABT-492 and other antimicrobials against Mycoplasma pneumoniae, Mycoplasma fermentans, Mycoplasma hominis, and Ureaplasma species. ABT-492 MICs were < or =1 microg/ml, and the agent was bactericidal against selected isolates of M. pneumoniae and M. hominis. ABT-492 has potential for treatment of infections due to these microorganisms.

545 Acta Endocrinologica (Buc), vol. X, no. 4, p. 545-558, 2014 *Correspondence to: Daniel Boda MD, PhD, “Carol Davila” University of Medicine and Pharmacy Dermatology Research Laboratory, 22-24 Gr. Manolescu, Sector 1, Bucharest, 0111234, Romania, E-mail: [email protected] Abstract Context. Melanoma is the most aggressive skin cancer, with significant morbidity and mortality, and one facto...

OBJECTIVES The in vitro activity of a new fluoroquinolone, ABT-492, was determined. METHODS MICs were compared with those of two beta-lactams, telithromycin, ciprofloxacin and four later generation fluoroquinolones. The effects of human serum and of inoculum concentration were also investigated. RESULTS MIC data indicate that ABT-492 has potent activity against Gram-positive organisms with ...

data parallelism for a decision tree, 489–492 data set structure, 479–480 decision tree algorithm, 480–481 decision tree classification, 477–480 processes, 480–488 structure, 478–479 result parallelism for the decision tree, 492–495

Endothelial cells growing in high glucose-containing medium show reduced cell proliferation and in vitro angiogenesis. Evidence suggests that the molecular pathways leading to these cellular responses are controlled by microRNAs, endogenous post-transcriptional regulators of gene expression. To identify the microRNAs and their targeted genes involved in the glucose responses, we performed the m...

Argrow, Brian 2000 Boulder Aerospace [email protected] [4] 303-492-0359 (Office) Armstrong, Gail 2017 Anschutz College of Nursing [email protected] [5] 303-724-8526 Averbach, Robert E. DDS (Emeritus) 1989 Anschutz Endodontics and Surgical Dentistry robert.averbach@ucdenver [6] 303-724-6970 (Office) Barth, Daniel 2004 Boulder Psychology [email protected] [7] ...

Argrow, Brian 2000 Boulder Aerospace [email protected] [4] 303-492-0359 (Office) Armstrong, Gail 2017 Anschutz College of Nursing [email protected] [5] 303-724-8526 Averbach, Robert E. DDS (Emeritus) 1989 Anschutz Endodontics and Surgical Dentistry robert.averbach@ucdenver [6] 303-724-6970 (Office) Barth, Daniel 2004 Boulder Psychology [email protected] [7] ...

527 percentiles calculated. 2 Applying the BSAC formula 4 to pharmaco-kinetic data (C max of ∼3.2 mg/L following an oral dose of 250 mg with a terminal half-life of 7–8 h), an MIC susceptible breakpoint (BP) of 0.4 mg/L was calculated. MIC data were reviewed to ascertain the ABT-492 MIC ranges for the 'wild sensitive' populations. For Enterobacteriaceae, In the case of staphylococci, the MIC ra...

Objectives. To evaluate the sperm chromatin dispersion in men with infertility using first Russian kit. Methods. The study was conducted between July and August 2022. Study participants were 492 male volunteers aged 23 to 59 years which semen samples examined by GEMSTANDART–HaloSperm L&amp;Q kit so-called Halo test. outcomes as a percentage DNA Fragmentation Index (DFI), %. results of test eval...

ABT-492 exhibited excellent in vitro activities against all 326 aerobic and anaerobic antral puncture sinus isolates tested with MICs (in micrograms per milliliter) at which 90% of the isolates tested were inhibited as follows: Haemophilus influenzae, 0.001; Moraxella catarrhalis, 0.008; and Streptococcus pneumoniae, 0.015. It was four- to sixfold more active than other fluoroquinolones, includ...