Fungal infections cause significant morbidity and mortality in immunocompromised patients. Oral candidosis is the most common opportunistic infection in human patients infected with HIV and AIDS. , 2 Paralleling the increased prevalence of fungal infections has been the introduction of new antifungal agents and the recognition of resistance. The chronic use of azoles for prophylaxis in systemic...

In lantibiotic lacticin 481 biosynthesis, LctT cleaves the precursor peptide and exports mature lantibiotic. Matrix-assisted laser desorption ionization-time of flight mass spectrometry revealed that a truncated form of lacticin 481 is produced in the absence of LctT or after cleavage site inactivation. Production of truncated lacticin 481 is 4-fold less efficient, and its specific activity is ...

Lantibiotics are ribosomally synthesized and post-translationally modified peptide natural products that contain the thioether structures lanthionine and methyllanthionine and exert potent antimicrobial activity against Gram-positive bacteria. At present, detailed modes-of-action are only known for a small subset of family members. Lacticin 481, a tricyclic lantibiotic, contains a lipid II bind...

5.1. Detection Formats 475 5.2. Food Quality and Safety Analysis 477 5.2.1. Pathogens 477 5.2.2. Toxins 479 5.2.3. Veterinary Drugs 479 5.2.4. Vitamins 480 5.2.5. Hormones 480 5.2.6. Diagnostic Antibodies 480 5.2.7. Allergens 481 5.2.8. Proteins 481 5.2.9. Chemical Contaminants 481 5.3. Medical Diagnostics 481 5.3.1. Cancer Markers 481 5.3.2. Antibodies against Viral Pathogens 482 5.3.3. Drugs ...

180 © 2011 Johnson Matthey doi:10.1595/147106711X581350 http://www.platinummetalsreview.com/ Edited by Pierluigi Barbaro and Francesca Liguori (Istituto di Chimica dei Composti Organo Metallici, Firenze, Italy), Springer, Dordrecht, The Netherlands, 2010, 459 pages, ISBN: 978-90-481-3695-7, £126.00, €139.95, US$189.00 (Print version); e-ISBN: 978-90-481-3694-4, doi:10.1007/978-90-481-3696-4 (On...

د ماعتملا فعاضملا يددر تلا مي سقتلا ما ظنل أ طخلا لد عم بسح ءادلاا (OFDM) يلضافت ريف شتل مدختسملا عو ن 16 يمجنلا د ماعتم يراد قم نيمضتب (QAM) نماز تم يلضافت فشاآو هيسواآ هفاضم ءاضيب ءاضوض تاذ ل قن ةا نقو ا ع يزوتل نيراسمب توفخ تاذ ىرخاو حطسم ددرت تاذ ةانقو صخلملا : ت نا يف لمعتسأٌ د ماعتملا فعاضملا يددر تلا مي سقتلا مسأب فورعملا ةددعتملا ةلماحلا تاددرتلا وذ لاسرلاا ةينق تانيتسلا دقع ) 1960's...