DL 473 is a 3-[(4-cyclopentyl-1-piperazinyl)iminomethyl] rifamycin SV derivative which inhibited staphylococci, streptococci (including Streptococcus faecalis, Listeria species, and Bacteroides species. DL 473 was less active than rifampin against these species. DL 473 did not inhibit Enterobacteriaceae nor most Pseudomonas species. A combination of DL 473 and vancomycin or nafcillin tested aga...

We derive asymptotics for the moments of the height distribution of watermelons with p branches with wall. This generalises a famous result by de Bruijn, Knuth and Rice [2] on the average height of planted plane trees, and a result by Fulmek [6] on the average height of watermelons with two branches.

To determine if different graded word lists can be used interchangeably for assessment purposes, and to determine if age, grade, or sex affects performance on the different graded word lists, a study examined the Wide Range Achievement Test (WRAT), Levels I and II, the San Diego Quick Assessment, and the Graded Word Reading Test by F.J. Schonell. The three lists were administered to 283 pupils ...

The susceptibilities of 20 clinical isolates of Mycobacterium intracellulare to rifampin, MDL 473, and ansamycin were determined by broth and agar dilution methods. Ansamycin was more active than MDL 473, which in turn was usually more active than rifampin by either method. The MICs for 90% of the strains tested by agar dilution were 1, 2, and 4 micrograms of ansamycin, MDL 473, and rifampin pe...

Full activation of protein kinase B (PKB, also called Akt) requires phosphorylation on two regulatory sites, Thr-308 in the activation loop and Ser-473 in the hydrophobic C-terminal regulatory domain (numbering for PKB alpha/Akt-1). Although 3'-phosphoinositide-dependent protein kinase 1 (PDK1) has now been identified as the Thr-308 kinase, the mechanism of the Ser-473 phosphorylation remains c...

In this study, the cytogenetic effects of a sulphonylurea group herbicide Logran (effective substance; Triasulfuron) were investigated in human peripheral blood lymphocyte culture. The cultures were treated with 2, 4, 8, 16, 32, 64, 128, and 256 mg/ml concentrations of Logran for 24 and 48 h. This compound increased chromosome aberrations (CA) in human lymphocyte culture. Logran decreased Mitot...