The focus of this study was the empirical modelling high-speed bearings life and failure modes a through-flow universal motor. An approach used facilitating predictions through-range various conditions. model estimates bearing for survival probability 50% – L50. It influences parameters such as temperature, speed factor, equivalent load, grease fill amount, type oil, cage, seals, tolerance clas...

Using the human lymphoblastoid cell line, GM 4672, and PBL of Gambian adults immune to Plasmodium falciparum (Pf) malaria, we have produced human-human hybridomas and selected those that produce mAb against Pf antigens. The fusion frequency, using PWM-stimulated donor lymphocytes was between 6.8 X 10(-5) and 1.5 X 10(-6). Using immune fluorescence, immune precipitation, and Pf in vitro growth i...

Tonsillar lymphocytes from an otherwise healthy nonthrombocytopenic male child were fused with the lymphoblastoid cell line GM 4672. Twenty of 472 (4%) hybridomas had antiplatelet reactivity detected using intact platelets in an enzyme-linked immunosorbent assay. One hybridoma (STO 171) reacted to platelet glycoprotein IIb (integrin alpha IIb) as determined by radioimmunoprecipitation and immun...

This study represents an initial attempt to analyze the humoral immune reactions of patients with malignant melanoma by hybridoma methodology. Using lymphocytes from regional lymph nodes, peripheral blood and tumor infiltrates, 158 fusions were performed with SKO-007 (human myeloma line), LICR-LON-HMy2 (LICR-2), GM 4672 (human lymphoblastoid lines), or NS-1 (mouse myeloma line). Fusion of lymph...

Alu-mediated rearrangement of tumor suppressor genes occurs frequently during carcinogenesis. In breast cancer, this mechanism contributes to loss of the wild-type BRCA1 allele in inherited disease and to loss of heterozygosity in sporadic cancer. To identify genes required for suppression of Alu-mediated recombination we performed a genomewide screen of a collection of 4672 yeast gene deletion...

BackgroundThis study aimed to (i) identify high-risk suicide-methods clusters, based on location of residence and suicide incidence; (ii) compare the characteristics cases spatial units inside outside clusters.MethodsSuicide data 4672 was obtained from Coroner's Court reports in Hong Kong (2014–2018). Monthly aggregated numbers residence, incidence, were small tertiary planning (STPUs). Communi...

Cold stress significantly constrains the growth, development, productivity, and distribution of rice, particularly indica cultivar, known for its susceptibility to cold, limiting cultivation specific regions. This study investigated genes associated with cold responsiveness in roots two cultivars, SQSL (cold-tolerant) XZX45 (cold-susceptible), through transcriptome dynamics analysis during seed...

Published studies world wide demonstrate that measures of human development and health status vary depending on the month of birth but these patterns are not always consistent and sometimes even conflict. Direct factors related to the birth season that may significantly differentiate morphological and functional traits and mechanisms causing these relations have not been found so far. On the ba...

BACKGROUND Recently, the Data collection of Adverse events of Anti-HIV Drugs Group (D:A:D) described results from their international observational cohort of 33,347 HIV-1-infected individuals, suggesting unexpected increased risk of myocardial infarction (MI) associated with abacavir (ABC) therapy [relative rate 1.9, 95% confidence interval (CI): 1.47 to 2.45; P = 0.0001]. To contribute to the ...

BACKGROUND Knowledge production and evaluation are two important functions of health research system (HRS). In this article, we aimed to reveal the correlation between evaluation of health research organizations and health knowledge production promotion. METHODS A comprehensive evaluation system was developed to evaluate the academic performance of national medical science universities on an ...