Previous studies have demonstrated that depletion of Gas7 impedes neurite outgrowth in primary cultures of Purkinje neurons, and that Gas7 promotes neurite outgrowth in PC12 cells. To investigate the physiological function of Gas7, we generated by homologous recombination a Gas7-mutant mouse which produced a Gas7 variant protein with an in-frame deletion of amino acid residues 103–120. Only low...

Utilization of renewable energy as a source electrical is an environmentallyfriendly development, one which the use solar by developing PV onthe roof buildings medium for installing modules. In this study, rooftop PVplan was carried out at Nangka Utara gas station whichaims to reduce cost PLN electricity bills. The system Utaragas uses On-grid without batteries, using 36 units 415 Wpmonocrystal...

We made substantial advances in the implementation of a rapamycin-triggered heterodimerization strategy. Using molecular engineering of different targeting and enzymatic fusion constructs and a new rapamycin analog, Rho GTPases were directly activated or inactivated on a timescale of seconds, which was followed by pronounced cell morphological changes. As signaling processes often occur within ...

Aedes albopictus is the most invasive mosquito in the world, an important disease vector, and a biting nuisance that limits outdoor activities. Area-wide integrated pest management (AW-IPM) is the recommended control strategy. We conducted an economic evaluation of the AW-IPM project in Mercer and Monmouth Counties, New Jersey with a controlled design (AW-IPM vs. control) from 2009 through 2011...

BACKGROUND & OBJECTIVES An outbreak of influenza was investigated between June 24 and July 30, 2009 in a residential school at Panchgani, Maharashtra, India. The objectives were to determine the aetiology, study the clinical features in the affected individuals and, important epidemiological and environmental factors. The nature of public health response and effectiveness of the control measure...

This study evaluated bacterial etiology and antibiotic susceptibility in patients diagnosed with community-acquired perforated appendicitis over a 12-year-period. We retrospectively reviewed records of adult patients diagnosed with perforated appendicitis at an 800-bed teaching hospital between January 2000 and December 2011. In total, 415 culture-positive perforated appendicitis cases were ana...