نتایج جستجو برای: 4 triazolidine

تعداد نتایج: 1303597  

Journal: :ACS infectious diseases 2017
Brendan W Corey Mitchell G Thompson Lauren E Hittle Anna C Jacobs Edward A Asafo-Adjei William M Huggins Roberta J Melander Christian Melander Robert K Ernst Daniel V Zurawski

Acinetobacter baumannii are Gram-negative bacilli that pose a constant threat to susceptible patients because of increased resistance to multiple antibiotics and persistence in the hospital environment. After genome analysis, we discovered that A. baumannii harbors genes that share homology to an enzymatic pathway that elongates long-chain fatty acids (LCFA) in fungi. Previously, 1,2,4-triazoli...

Journal: :journal of reports in pharmaceutical sciences 0
hadi  adibi department of medicinal chemistry, faculty of pharmacy, kermanshah university of medical sciences, kermanshah 67145-1673, iran leila hosseizadeh maryam mahdian alireza foroumadi mohammad ali zolfigol shadpour mallakpour

a series of fluoroquinolone derivatives holding triazolidindione moieties have been synthesized and proved to be cytotoxic agents in vitro particularly against cancer cell lines (sknmc, mcf7, a2780-cp, sw48, a549, kb, ht-29, hepg 2 ). the cytotoxic activity was assessed using mtt colorimetric assay. our compounds had less cytotoxicity than doxorubicin in all studied cell lines.

Journal: :Acta Crystallographica Section E Structure Reports Online 2011

Journal: :Acta Crystallographica Section E Structure Reports Online 2010

Journal: :Acta Crystallographica Section E Structure Reports Online 2012

Journal: :Acta Crystallographica Section E Structure Reports Online 2011

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