X-ray repair cross complementing group 1 (XRCC1) encodes a protein involved in base excision repair. We examined the association of polymorphisms in XRCC1 (codon 194 Arg-->Trp and codon 399 Arg-->Gln) and breast cancer in the Carolina Breast Cancer Study, a population-based case-control study in North Carolina. No association was observed between XRCC1 codon 194 genotype and breast cancer, and ...

iDepartment of Dental Materials, Matsumoto Dentat UniversiCn t780 Gobara, Hirooka Shiojiri, Nagano 399-O187, Japan 2Division of Biomaterials, Department of Hard TTssue Research, Graduate Schoot of Orei Medicine, Matsumoto Dental UniversiCn f180 Gobara, Hirooka Shiojiri, Nagano 399-078V, Japan 3Division oflmptantologx tnstitute for Oral Science, Matsumoto Dentai UniversiCx t780 Gobara, Hirooka S...

Equilibrium dialysis of concanavalin A against methyl c¢-D-mannopyranoside and methyl C¢-D-glucopyranoside conducted at 2 ° in the presence of I M NaC1 showed that concanavalin A is bivalent. A SCATCHARD plot of the data obtained gave straight lines for both sugars with observed association constants (K') of 1. 4. lO 4 1/mole for methyl ,¢-D-mannopyranoside and o.3" IO 4 1/mole for methyl ~¢-D-...

IntroductionInvasive fungal diseases are crucial causes of morbidity and mortality among patients with febrile neutropenia (FN). Though liposomal amphotericin B (L-AMB) is one the agents recommended for first-line empirical antifungal therapy in FN, large-scale clinical studies have not been performed Japan.MethodsAn open-label prospective multi-center study was carried out to evaluate safety e...

Abstract The presentation will correlate mostly to pet food and cover the fundamentals freeze drying, importance of recipe development, different freeze-drying applications, product yield factors for advantages parameters key aspects dryers, some examples meat drying profiles trends.

XRCC1-399 allele polymorphisms have been reported to be associated with susceptibility to hepatocellular carcinoma (HCC), but the conclusions of the various studies have been inconsistent. We conducted a meta-analysis of available studies to determine whether XRCC1-399 alleles influence susceptibility to hepatocellular carcinoma. We searched English-language databases, including PubMed, Medline...

Routine in vitro screening of a new synthetic series of 3,5-substituted 2-methylisoxazolidines revealed that three imidazole analogs (PR 967-248, PR 967-234, and PR 969-566) and, to a lesser extent, a triazole analog (PR 988-399) exerted rather potent antifungal activity against three systemic and four dermatophytic classes of fungi. When tested in vivo for ability to eradicate Candida vaginiti...

The authors studied whether the drawing variability in young children is best explicable by (a) demands on the explicit timing system, (b) an underdeveloped ability to control limb dynamics, or (c) both. The explicit timing demands were lower in continuous drawing in comparison with the discontinuous task. The authors manipulated limb dynamics by changing the number of joints involved, with lin...